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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL325536
Molecular formula	C27H27ClF3NO
IUPAC name	4-[4-chloro-3-(trifluoromethyl)phenyl]-1-(3,3-diphenylpropyl)piperidin-4-ol
Molecular weight	473.964
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	6.7
Synonyms	1-(3,3-Diphenylpropyl)-4-[3-(trifluoromethyl)-4-chlorophenyl]piperidine-4-ol BDBM50132644 4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(3,3-diphenyl-propyl)-piperidin-4-ol
Inchi Key	WUTNCUOBFDCXMO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H27ClF3NO/c28-25-12-11-22(19-24(25)27(29,30)31)26(33)14-17-32(18-15-26)16-13-23(20-7-3-1-4-8-20)21-9-5-2-6-10-21/h1-12,19,23,33H,13-18H2
PubChem CID	44339374
ChEMBL	CHEMBL325536
IUPHAR	N/A
BindingDB	50132644
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
382902	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
382903	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370
382904	Nociceptin receptor	P35370	Oprl1	Rattus norvegicus (Rat)	367

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