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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Nociceptin receptor
Species	Rattus norvegicus (Rat)
Gene	Oprl1
Synonym	NOP receptor NOP-r NOPr OP4 Orphanin FQ receptor ROR-C NOCIR nociceptin/orphanin FQ receptor nociceptin receptor ORL1 N/OFQ receptor MOR-C KOR-3 kappa3-related opioid receptor Kappa-type 3 opioid receptor XOR1 [ Show all ]
Disease	N/A for non-human GPCRs
Length	367
Amino acid sequence	MESLFPAPYWEVLYGSHFQGNLSLLNETVPHHLLLNASHSAFLPLGLKVTIVGLYLAVCIGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPAPQDYWGPVFAICIFLFSFIIPVLIISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLVQGLGVQPGSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASSLHREMQVSDRVRSIAKDVGLGCKTSETVPRPA
UniProt	P35370
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4503
IUPHAR	320
DrugBank	N/A

Ligand

Name	CHEMBL325536
Molecular formula	C27H27ClF3NO
IUPAC name	4-[4-chloro-3-(trifluoromethyl)phenyl]-1-(3,3-diphenylpropyl)piperidin-4-ol
Molecular weight	473.964
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	6.7
Synonyms	1-(3,3-Diphenylpropyl)-4-[3-(trifluoromethyl)-4-chlorophenyl]piperidine-4-ol BDBM50132644 4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(3,3-diphenyl-propyl)-piperidin-4-ol
Inchi Key	WUTNCUOBFDCXMO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H27ClF3NO/c28-25-12-11-22(19-24(25)27(29,30)31)26(33)14-17-32(18-15-26)16-13-23(20-7-3-1-4-8-20)21-9-5-2-6-10-21/h1-12,19,23,33H,13-18H2
PubChem CID	44339374
ChEMBL	CHEMBL325536
IUPHAR	N/A
BindingDB	50132644
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Activity	<10.0 %	PMID15454210	ChEMBL

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