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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1783826
Molecular formula	C26H33Cl2N3O
IUPAC name	(2R)-1-benzyl-N-[3-[4-(2,6-dichlorophenyl)piperidin-1-yl]propyl]pyrrolidine-2-carboxamide
Molecular weight	474.47
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.5
Synonyms	DGV 1-Benzyl-N-{3-[4-(2,6-Dichlorophenyl)piperidin-1-Yl]propyl}-D-Prolinamide SCHEMBL8178272 1-benzyl-N-(3-[4-(2,6-dichlorophenyl)piperidin-1-yl]propyl)-d-prolinamide BDBM50418594
Inchi Key	UWHDLFOAIARROU-XMMPIXPASA-N
Inchi ID	InChI=1S/C26H33Cl2N3O/c27-22-9-4-10-23(28)25(22)21-12-17-30(18-13-21)15-6-14-29-26(32)24-11-5-16-31(24)19-20-7-2-1-3-8-20/h1-4,7-10,21,24H,5-6,11-19H2,(H,29,32)/t24-/m1/s1
PubChem CID	25001412
ChEMBL	CHEMBL1783826
IUPHAR	N/A
BindingDB	50418594
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
347278	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
347272	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
347275	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
347273	Nociceptin receptor	P35377	Oprl1	Mus musculus (Mouse)	367
347274	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370
347276	Nociceptin receptor	P35370	Oprl1	Rattus norvegicus (Rat)	367
347277	Nociceptin receptor	P47748	OPRL1	Cavia porcellus (Guinea pig)	370

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