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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	nociceptin(1-13)NH2
Molecular formula	C61H100N22O15
IUPAC name	(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S,3R)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-phenylpropanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-3-hydroxypropanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanamide
Molecular weight	1381.61
Hydrogen bond acceptor	20
Hydrogen bond donor	22
XlogP	-7.0
Synonyms	OFQ/N (1-11) D0Z2XW NCGC00167157-01 BDBM50106479 GTPL1682 Nociceptin Orphanin FQ..1-13..-NH..2.. nociceptin/orphanin FQ(1-13)NH2 178064-02-3 CHEMBL384755 N/OFQ-(1-13)-NH2 orphanin FQ(1-13)NH2 AC1O44IO Demethyl-AMPA Nociceptin (1-13)NH2 BDBM85822 H-FGGFTGARKSARK-NH2 nociceptin(1-13)-NH2 OFQ/N D0Y4EW NC(1-13)NH2 Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-NH2 AKOS024456547 FGGFTGARKSARK Nociceptin analogueNC(1-13)-NH2 N/OFQ(1-13)NH2 [ Show all ]
Inchi Key	RHMALYOXPBRJBG-CGUXNFSNSA-N
Inchi ID	InChI=1S/C61H100N22O15/c1-34(75-47(87)32-74-59(98)49(36(3)85)83-57(96)44(29-38-18-8-5-9-19-38)77-48(88)31-72-46(86)30-73-53(92)39(64)28-37-16-6-4-7-17-37)51(90)79-43(23-15-27-71-61(68)69)55(94)81-41(21-11-13-25-63)56(95)82-45(33-84)58(97)76-35(2)52(91)80-42(22-14-26-70-60(66)67)54(93)78-40(50(65)89)20-10-12-24-62/h4-9,16-19,34-36,39-45,49,84-85H,10-15,20-33,62-64H2,1-3H3,(H2,65,89)(H,72,86)(H,73,92)(H,74,98)(H,75,87)(H,76,97)(H,77,88)(H,78,93)(H,79,90)(H,80,91)(H,81,94)(H,82,95)(H,83,96)(H4,66,67,70)(H4,68,69,71)/t34-,35-,36+,39-,40-,41-,42-,43-,44-,45-,49-/m0/s1
PubChem CID	6324645
ChEMBL	CHEMBL384755
IUPHAR	1682
BindingDB	85822, 50106479
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
296315	Nociceptin receptor	P35377	Oprl1	Mus musculus (Mouse)	367
296316	Nociceptin receptor	P35370	Oprl1	Rattus norvegicus (Rat)	367
296317	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370
296318	Nociceptin receptor	P79292	OPRL1	Sus scrofa (Pig)	370

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