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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL427007
Molecular formula	C25H23BrN2O3
IUPAC name	8-[[(2S,4S,6S)-17-bromo-3,13-dioxatetracyclo[12.4.0.02,6.07,12]octadeca-1(14),7,9,11,15,17-hexaen-4-yl]methyl]-N,N-dimethyl-7-oxa-8-azabicyclo[4.2.0]octa-1(6),2,4-trien-3-amine
Molecular weight	479.374
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	5.3
Synonyms	BDBM50167761 [8-((2S,3aS,12bS)-11-Bromo-2,3,3a,12b-tetrahydro-1,8-dioxa-dibenzo[e,h]azulen-2-ylmethyl)-7-oxa-8-aza-bicyclo[4.2.0]octa-1(6),2,4-trien-3-yl]-dimethyl-amine
Inchi Key	UFVZMDZVXDJFLY-KMEZTADASA-N
Inchi ID	InChI=1S/C25H23BrN2O3/c1-27(2)16-8-10-24-21(12-16)28(31-24)14-17-13-19-18-5-3-4-6-22(18)30-23-9-7-15(26)11-20(23)25(19)29-17/h3-12,17,19,25H,13-14H2,1-2H3/t17-,19-,25-/m0/s1
PubChem CID	44402566
ChEMBL	CHEMBL427007
IUPHAR	N/A
BindingDB	50167761
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
335889	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
335888	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
335887	Nociceptin receptor	P35370	Oprl1	Rattus norvegicus (Rat)	367

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