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Name | Somatostatin receptor type 2 |
---|---|
Species | Mus musculus (Mouse) |
Gene | Sstr2 |
Synonym | somatotropin release-inhibiting factor receptor SRIF-1 SS-2-R SS2-R SS2R [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 369 |
Amino acid sequence | MEMSSEQLNGSQVWVSSPFDLNGSLGPSNGSNQTEPYYDMTSNAVLTFIYFVVCVVGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWCVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSVAISPTPALKGMFDFVVILTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTEDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI |
UniProt | P30875 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3207 |
IUPHAR | 356 |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
555548 | BDBM84629 | C71H81N11O9 | 1232.5 | 11 / 12 | 8.1 | No |
555554 | SA V | C46H62N8O6 | 823.052 | 8 / 8 | 4.6 | No |
555593 | SA II | C38H54N8O6 | 718.9 | 8 / 9 | 2.6 | No |
555627 | L-362855 | C57H70N10O8 | 1023.25 | 9 / 11 | 5.7 | No |
555651 | BDBM82458 | C52H68N10O9 | 977.177 | 11 / 12 | 3.4 | No |
555663 | CHEMBL268112 | C67H79N11O9 | 1182.44 | 11 / 12 | 5.6 | No |
555674 | BDBM84620 | C54H70N10O10S2 | 1083.33 | 14 / 13 | 2.9 | No |
443978 | CHEMBL3350037 | C49H66N10O10S2 | 1019.25 | 14 / 13 | 1.0 | No |
555692 | Octreotide | C49H66N10O10S2 | 1019.25 | 14 / 13 | 1.0 | No |
58033 | Octreotide | C49H66N10O10S2 | 1019.25 | 14 / 13 | 1.0 | No |
553532 | Octreotide | C49H66N10O10S2 | 1019.25 | 14 / 13 | 1.0 | No |
555695 | BDBM82466 | C55H68ClN9O8 | 1018.65 | 9 / 10 | 6.2 | No |
555710 | CHEMBL2369699 | C43H59N9O8S2 | 894.12 | 11 / 10 | 2.1 | No |
555728 | BDBM84640 | C71H80ClN11O9 | 1266.94 | 11 / 12 | 8.8 | No |
68359 | CHEMBL436783 | C49H65N11O10S | 1000.19 | 13 / 13 | 0.5 | No |
555774 | CHEMBL421362 | C44H54N8O7 | 806.965 | 8 / 8 | 3.4 | No |
93067 | CHEMBL69379 | C45H57N9O9S | 900.065 | 12 / 11 | -0.2 | No |
555827 | BDBM82460 | C137H207N41O39S3 | 3148.59 | 48 / 44 | -16.0 | No |
553729 | Somatostatin 28 | C137H207N41O39S3 | 3148.59 | 48 / 46 | -15.2 | No |
555882 | BDBM84625 | C49H67N11O10 | 970.142 | 12 / 13 | -0.5 | No |
555884 | BDBM84623 | C55H64N10O9S2 | 1073.3 | 13 / 12 | 3.8 | No |
114083 | CHEMBL147319 | C32H41N5O4 | 559.711 | 5 / 4 | 3.9 | No |
555927 | BDBM84628 | C56H66N10O8S2 | 1071.33 | 12 / 11 | 4.6 | No |
555935 | BIM 23052 | C61H75N11O10 | 1122.34 | 12 / 13 | 2.7 | No |
555965 | BDBM82467 | C73H99N15O18 | 1474.68 | 20 / 20 | -0.8 | No |
555990 | BDBM84624 | C61H74ClN11O11 | 1172.78 | 13 / 14 | 3.7 | No |
128918 | CHEMBL146128 | C30H39N5O2 | 501.675 | 3 / 4 | 4.0 | No |
556042 | BIM-23023 | C49H65N11O10S2 | 1032.25 | 14 / 13 | 0.8 | No |
556061 | BIM 23268 | C54H67N11O9S2 | 1078.32 | 13 / 12 | 2.8 | No |
556090 | BDBM84644 | C44H58N8O6 | 794.998 | 8 / 8 | 3.6 | No |
166626 | CHEMBL421493 | C45H57N9O9S2 | 932.125 | 13 / 11 | -0.2 | No |
167139 | CHEMBL415860 | C49H64N10O11S2 | 1033.23 | 15 / 13 | -1.1 | No |
556161 | BDBM82454 | C44H56N8O7 | 808.981 | 8 / 7 | 3.4 | No |
556163 | BDBM84617 | C60H74ClN11O8 | 1112.77 | 10 / 11 | 6.5 | No |
556215 | BDBM84616 | C47H62ClN9O8 | 916.518 | 10 / 10 | 2.5 | No |
556216 | BDBM85230 | C54H69N11O9S2 | 1080.33 | 13 / 14 | 2.3 | No |
186163 | CHEMBL266469 | C49H64N10O11S | 1001.17 | 14 / 13 | -1.1 | No |
556276 | SA IV | C44H58N8O6 | 794.998 | 8 / 8 | 3.5 | No |
223705 | SOMATOSTATIN | C76H104N18O19S2 | 1637.9 | 24 / 22 | -3.1 | No |
556356 | SOMATOSTATIN | C76H104N18O19S2 | 1637.9 | 24 / 22 | -3.1 | No |
554413 | seglitide | C44H56N8O7 | 808.981 | 8 / 8 | 3.9 | No |
556374 | CHEMBL413535 | C44H56N8O7 | 808.981 | 8 / 8 | 3.9 | No |
556376 | BDBM81766 | C44H56N8O7 | 808.981 | 8 / 8 | 3.9 | No |
556482 | CHEMBL3349593 | C38H50N8O7 | 730.867 | 8 / 8 | 1.8 | No |
556490 | BIM-23058 | C62H77N11O10 | 1136.36 | 12 / 13 | 4.7 | No |
556522 | Lanreotide | C54H69N11O10S2 | 1096.33 | 14 / 13 | 2.5 | No |
554605 | Lanreotide acetate | C54H69N11O10S2 | 1096.33 | 14 / 13 | 2.5 | No |
556546 | BDBM84619 | C69H83ClN12O13 | 1323.94 | 15 / 16 | 4.1 | No |
556617 | BDBM82462 | C54H68N12O12S2 | 1141.33 | 15 / 15 | 1.5 | No |
299000 | CHEMBL146022 | C32H40N4O5 | 560.695 | 6 / 3 | 4.5 | No |
308753 | CHEMBL1791313 | C65H92N14O18S2 | 1421.65 | 25 / 17 | -7.2 | No |
556742 | BIM-23027 | C43H54N8O7 | 794.954 | 8 / 8 | 3.5 | No |
556793 | Vapreotide | C57H70N12O9S2 | 1131.38 | 13 / 13 | 3.6 | No |
556802 | CH-275 | C74H96N14O15S2 | 1485.79 | 20 / 18 | 1.6 | No |
556838 | BDBM82461 | C59H73N11O9 | 1080.3 | 11 / 12 | 5.0 | No |
556893 | SCHEMBL1579410 | C62H76ClN11O10 | 1170.81 | 12 / 13 | 5.3 | No |
556896 | CHEMBL3350185 | C62H76N12O12 | 1181.36 | 14 / 13 | 4.5 | No |
346567 | CHEMBL306702 | C36H48N8O8S | 752.888 | 11 / 10 | -1.6 | No |
556903 | cycloantagonist SA | C42H55N7O5 | 737.946 | 7 / 7 | 4.8 | No |
556955 | BDBM84626 | C55H64N10O8S2 | 1057.3 | 12 / 11 | 4.3 | No |
556979 | BIM 23056 | C71H81N11O9 | 1232.5 | 11 / 12 | 8.1 | No |
556980 | BDBM84621 | C61H69N11O9S2 | 1164.41 | 13 / 12 | 6.1 | No |
555100 | SS14 | C63H88N16O16S2 | 1389.61 | 21 / 19 | -4.1 | No |
381832 | CHEMBL2069502 | C25H26N4O | 398.51 | 3 / 3 | 3.5 | Yes |
557084 | BDBM84630 | C56H66N10O9S2 | 1087.32 | 13 / 12 | 4.2 | No |
557118 | BDBM82456 | C45H57N9O8S2 | 916.126 | 11 / 10 | 3.0 | No |
394310 | CHEMBL144146 | C31H41N5O2 | 515.702 | 3 / 3 | 4.1 | No |
557137 | BDBM84627 | C56H72ClN11O9 | 1078.71 | 11 / 12 | 4.2 | No |
557154 | CHEMBL264562 | C61H74ClN11O9 | 1140.78 | 11 / 12 | 5.1 | No |
557211 | Bim-23003 | C71H95ClN16O17S2 | 1544.21 | 22 / 20 | -1.6 | No |
557265 | BDBM85229 | C54H69N11O10S2 | 1096.33 | 14 / 15 | 2.0 | No |
557280 | BDBM84638 | C58H71N11O10 | 1082.27 | 12 / 13 | 3.4 | No |
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