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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	seglitide
Molecular formula	C44H56N8O7
IUPAC name	(3S,6S,9S,12R,15S,18S)-9-(4-aminobutyl)-3-benzyl-15-[(4-hydroxyphenyl)methyl]-12-(1H-indol-3-ylmethyl)-1,18-dimethyl-6-propan-2-yl-1,4,7,10,13,16-hexazacyclooctadecane-2,5,8,11,14,17-hexone
Molecular weight	808.981
Hydrogen bond acceptor	8
Hydrogen bond donor	8
XlogP	3.9
Synonyms	Cyclic (N-Me-Ala-Tyr-D-Trp-Lys-Val-Phe) L-363586 Seglitida (3S,6S,9S,12R,15S,18S)-12-((1H-indol-3-yl)methyl)-9-(4-aminobutyl)-3-benzyl-15-(4-hydroxybenzyl)-6-isopropyl-1,18-dimethyl-1,4,7,10,13,16-hexaazacyclooctadecane-2,5,8,11,14,17-hexaone 99248-33-6 (monoacetate) cyclo(N-Me-Ala-Tyr-D-Trp-Lys-Val-Phe) MK-678 Seglitidum (3S,6S,9S,12R,15S,18S)-9-(4-aminobutyl)-3-benzyl-15-[(4-hydroxyphenyl)methyl]-12-(1H-indol-3-ylmethyl)-1,18-dimethyl-6-propan-2-yl-1,4,7,10,13,16-hexazacyclooctadecane-2,5,8,11,14,17-hexone BDBM50051568 EU-0101105 S 1316 UNII-5P57R7IR6J 5P57R7IR6J Cyclic(N-methyl-Ala-Tyr-D-Trp-Lys-Val-Phe) Lopac0_001105 (3S,6S,9S,12R,15S,18S)-9-(4-Amino-butyl)-3-benzyl-15-(4-hydroxy-benzyl)-12-(1H-indol-3-ylmethyl)-6-isopropyl-1,18-dimethyl-1,4,7,10,13,16hexaaza-cyclooctadecane-2,5,8,11,14,17-hexaone AC1NSKMC cyclo-(N-Me-Ala-Tyr-D-Trp-Lys-Val-Phe) MK678 SR-01000076118 C-23539 CHEMBL311695 GTPL2051 SCHEMBL151244 ZINC85537084 81377-02-8 Cyclo(D-Trp-Lys-Val-Phe-N-Me-Ala-Tyr) MK 678 Seglitide < Rec INN > (3S,6S,9S,12R,15S,18S)-9-(4-aminobutyl)-15-[(4-hydroxyphenyl)methyl]-12-(1H-indol-3-ylmethyl)-1,18-dimethyl-3-(phenylmethyl)-6-propan-2-yl-1,4,7,10,13,16-hexazacyclooctadecane-2,5,8,11,14,17-hexone AKOS024456805 D09JXL NPJIOCBFOAHEDO-AVWFULIKSA-N SR-01000076118-2 CCG-205181 [ Show all ]
Inchi Key	NPJIOCBFOAHEDO-AVWFULIKSA-N
Inchi ID	InChI=1S/C44H56N8O7/c1-26(2)38-43(58)50-37(23-28-12-6-5-7-13-28)44(59)52(4)27(3)39(54)48-35(22-29-17-19-31(53)20-18-29)41(56)49-36(24-30-25-46-33-15-9-8-14-32(30)33)42(57)47-34(40(55)51-38)16-10-11-21-45/h5-9,12-15,17-20,25-27,34-38,46,53H,10-11,16,21-24,45H2,1-4H3,(H,47,57)(H,48,54)(H,49,56)(H,50,58)(H,51,55)/t27-,34-,35-,36+,37-,38-/m0/s1
PubChem CID	5311430
ChEMBL	CHEMBL311695
IUPHAR	2051
BindingDB	50051568
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
228977	Somatostatin receptor type 1	P30872	SSTR1	Homo sapiens (Human)	391
228981	Somatostatin receptor type 2	P30680	Sstr2	Rattus norvegicus (Rat)	369
228984	Somatostatin receptor type 2	P30874	SSTR2	Homo sapiens (Human)	369
554413	Somatostatin receptor type 2	P30875	Sstr2	Mus musculus (Mouse)	369
228978	Somatostatin receptor type 3	P32745	SSTR3	Homo sapiens (Human)	418
554414	Somatostatin receptor type 3	P30935	Sstr3	Mus musculus (Mouse)	428
554415	Somatostatin receptor type 3	P30936	Sstr3	Rattus norvegicus (Rat)	428
228975	Somatostatin receptor type 4	P31391	SSTR4	Homo sapiens (Human)	388
228976	Somatostatin receptor type 5	P35346	SSTR5	Homo sapiens (Human)	364
554412	Somatostatin receptor type 5	O08858	Sstr5	Mus musculus (Mouse)	362
554416	Somatostatin receptor type 5	P30938	Sstr5	Rattus norvegicus (Rat)	363
228985	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407

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