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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Somatostatin receptor type 2
Species	Mus musculus (Mouse)
Gene	Sstr2
Synonym	somatotropin release-inhibiting factor receptor SRIF-1 SS-2-R SS2-R SS2R SST2 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	369
Amino acid sequence	MEMSSEQLNGSQVWVSSPFDLNGSLGPSNGSNQTEPYYDMTSNAVLTFIYFVVCVVGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWCVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSVAISPTPALKGMFDFVVILTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTEDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
UniProt	P30875
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3207
IUPHAR	356
DrugBank	N/A

Ligand

Name	BDBM84625
Molecular formula	C49H67N11O10
IUPAC name	(2S)-6-amino-N-[(2S)-1-[[(2S)-1-[[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanamide
Molecular weight	970.142
Hydrogen bond acceptor	12
Hydrogen bond donor	13
XlogP	-0.5
Synonyms	BIM 23051
Inchi Key	GVSJBZZGXKEBGH-KFMCEEOESA-N
Inchi ID	InChI=1S/C49H67N11O10/c1-27(54-45(66)35(51)23-31-15-7-5-8-16-31)43(64)57-38(24-32-17-9-6-10-18-32)47(68)58-39(25-33-26-53-36-20-12-11-19-34(33)36)48(69)56-37(21-13-14-22-50)46(67)60-41(30(4)62)49(70)55-28(2)44(65)59-40(29(3)61)42(52)63/h5-12,15-20,26-30,35,37-41,53,61-62H,13-14,21-25,50-51H2,1-4H3,(H2,52,63)(H,54,66)(H,55,70)(H,56,69)(H,57,64)(H,58,68)(H,59,65)(H,60,67)/t27-,28-,29+,30?,35+,37-,38-,39+,40-,41-/m0/s1
PubChem CID	57339790
ChEMBL	N/A
IUPHAR	N/A
BindingDB	84625
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Ki	836.0 nM	PMID8100350	BindingDB

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