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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Somatostatin receptor type 2
Species	Mus musculus (Mouse)
Gene	Sstr2
Synonym	somatotropin release-inhibiting factor receptor SRIF-1 SS-2-R SS2-R SS2R SST2 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	369
Amino acid sequence	MEMSSEQLNGSQVWVSSPFDLNGSLGPSNGSNQTEPYYDMTSNAVLTFIYFVVCVVGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWCVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSVAISPTPALKGMFDFVVILTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTEDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
UniProt	P30875
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3207
IUPHAR	356
DrugBank	N/A

Ligand

Name	CHEMBL147319
Molecular formula	C32H41N5O4
IUPAC name	methyl (2R)-6-amino-2-[[(2R)-3-(1H-indol-3-yl)-2-(spiro[1,2-dihydroindene-3,4'-piperidine]-1'-carbonylamino)propanoyl]amino]hexanoate
Molecular weight	559.711
Hydrogen bond acceptor	5
Hydrogen bond donor	4
XlogP	3.9
Synonyms	BDBM50075278 methyl 6-amino-2-[2-(1H-3-indolyl)-1-spiro[2,3-dihydro-1H-indene-1,4''-(hexahydropyridine)]-1-ylcarboxamido-(1R)-ethylcarboxamido]-(2R)-hexanoate
Inchi Key	HGHAEFXYQVJDKM-VSGBNLITSA-N
Inchi ID	InChI=1S/C32H41N5O4/c1-41-30(39)27(12-6-7-17-33)35-29(38)28(20-23-21-34-26-11-5-3-9-24(23)26)36-31(40)37-18-15-32(16-19-37)14-13-22-8-2-4-10-25(22)32/h2-5,8-11,21,27-28,34H,6-7,12-20,33H2,1H3,(H,35,38)(H,36,40)/t27-,28-/m1/s1
PubChem CID	44363921
ChEMBL	CHEMBL147319
IUPHAR	N/A
BindingDB	50075278
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Ki	2.0 nM	PMID10091708	BindingDB,ChEMBL

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