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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Somatostatin receptor type 2
Species	Mus musculus (Mouse)
Gene	Sstr2
Synonym	somatotropin release-inhibiting factor receptor SRIF-1 SS-2-R SS2-R SS2R SST2 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	369
Amino acid sequence	MEMSSEQLNGSQVWVSSPFDLNGSLGPSNGSNQTEPYYDMTSNAVLTFIYFVVCVVGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWCVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSVAISPTPALKGMFDFVVILTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTEDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
UniProt	P30875
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3207
IUPHAR	356
DrugBank	N/A

Ligand

Name	BDBM84621
Molecular formula	C61H69N11O9S2
IUPAC name	(6S,9S,12R,15S)-9-(4-aminobutyl)-N-(1-amino-3-naphthalen-2-yl-1-oxopropan-2-yl)-18-[(2-amino-3-naphthalen-2-ylpropanoyl)amino]-15-[(4-hydroxyphenyl)methyl]-12-(1H-indol-3-ylmethyl)-5,8,11,14,17-pentaoxo-6-propan-2-yl-1,2-dithia-4,7,10,13,16-pentazacyclooctadecane-3-carboxamide
Molecular weight	1164.41
Hydrogen bond acceptor	13
Hydrogen bond donor	12
XlogP	6.1
Synonyms	N/A
Inchi Key	VQIMHAVNZCCZNX-RYZOTEISSA-N
Inchi ID	InChI=1S/C61H69N11O9S2/c1-34(2)51-57(79)72-61(58(80)67-48(52(64)74)31-37-19-23-39-12-4-6-14-41(39)28-37)83-82-60(71-53(75)45(63)29-36-18-22-38-11-3-5-13-40(38)27-36)59(81)69-49(30-35-20-24-43(73)25-21-35)55(77)68-50(32-42-33-65-46-16-8-7-15-44(42)46)56(78)66-47(54(76)70-51)17-9-10-26-62/h3-8,11-16,18-25,27-28,33-34,45,47-51,60-61,65,73H,9-10,17,26,29-32,62-63H2,1-2H3,(H2,64,74)(H,66,78)(H,67,80)(H,68,77)(H,69,81)(H,70,76)(H,71,75)(H,72,79)/t45?,47-,48?,49-,50+,51-,60?,61?/m0/s1
PubChem CID	57339787
ChEMBL	N/A
IUPHAR	N/A
BindingDB	84621
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	4.2 nM	PMID8100350	BindingDB

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