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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Somatostatin receptor type 2
Species	Mus musculus (Mouse)
Gene	Sstr2
Synonym	somatotropin release-inhibiting factor receptor SRIF-1 SS-2-R SS2-R SS2R SST2 receptor [ Show all ]
Disease	N/A for non-human GPCRs
Length	369
Amino acid sequence	MEMSSEQLNGSQVWVSSPFDLNGSLGPSNGSNQTEPYYDMTSNAVLTFIYFVVCVVGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWCVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSVAISPTPALKGMFDFVVILTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTEDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
UniProt	P30875
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3207
IUPHAR	356
DrugBank	N/A

Ligand

Name	BDBM85230
Molecular formula	C54H69N11O9S2
IUPAC name	(2S)-6-amino-N-[(2R)-1-[[1-[(1-amino-1-oxo-3-sulfanylpropan-2-yl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]-2-[[(2R)-2-[[(2S)-2-[[2-[(2-amino-3-sulfanylpropanoyl)amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanamide
Molecular weight	1080.33
Hydrogen bond acceptor	13
Hydrogen bond donor	14
XlogP	2.3
Synonyms	BIM 23313
Inchi Key	LBRSAPKITPIKNC-NPCZSIKFSA-N
Inchi ID	InChI=1S/C54H69N11O9S2/c1-32(66)46(54(74)63-43(27-35-19-9-4-10-20-35)52(72)64-45(31-76)47(57)67)65-49(69)40(23-13-14-24-55)59-53(73)44(28-36-29-58-39-22-12-11-21-37(36)39)62-51(71)42(26-34-17-7-3-8-18-34)61-50(70)41(60-48(68)38(56)30-75)25-33-15-5-2-6-16-33/h2-12,15-22,29,32,38,40-46,58,66,75-76H,13-14,23-28,30-31,55-56H2,1H3,(H2,57,67)(H,59,73)(H,60,68)(H,61,70)(H,62,71)(H,63,74)(H,64,72)(H,65,69)/t32?,38?,40-,41?,42-,43?,44+,45?,46+/m0/s1
PubChem CID	57340027
ChEMBL	N/A
IUPHAR	N/A
BindingDB	85230
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Ki	4.78 nM	PMID9600011	BindingDB
Ki	115.0 nM	PMID9600011	BindingDB

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