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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	SOMATOSTATIN
Molecular formula	C76H104N18O19S2
IUPAC name	(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-37-[[2-[[(2S)-2-aminopropanoyl]amino]acetyl]amino]-13,25,28-tribenzyl-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecazacyclooctatriacontane-4-carboxylic acid
Molecular weight	1637.9
Hydrogen bond acceptor	24
Hydrogen bond donor	22
XlogP	-3.1
Synonyms	L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2 Somatostatin (human) Somatostatin-1 Somatotropin release inhibiting factor CAS_38916-34-6 MFCD00076762 Somatostatin (sheep) Somatostatina [INN-Spanish] Synthetic cyclic growth hormone release-inhibiting factor 38916-34-6 AKOS015994634 CHEBI:64628 Growth hormone release inhibiting factor H664 NHXLMOGPVYXJNR-ATOGVRKGSA-N Somatostatin [INN:BAN] Somatostatinum UNII-6E20216Q0L 55914-64-2 BRD-K14681867-015-01-6 Cyclic Somatostatin L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine cyclic (3-14) disulfide Somatostatin (pigeon) Somatostatin-14 SR 9357 916S346 CB6417646 EINECS 254-186-5 Growth hormone-release inhibiting factor: L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine cyclic (3-14) disulfide MolPort-006-823-896 Somatostatin acetate Somatostatine Synthetic growth hormone release-inhibiting hormone 51110-01-1 (Parent) Ala-Gly-cyclo-[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys] HS-2027 Somatostatin, cyclic Somatostatinum [INN-Latin] UNII-F6R2N217HS 6E20216Q0L C76H104N18O19S2 D0T5RO LS-174755 Somatostatin (rat) Somatostatina SRIF 15-28-Somatostatin-28 AK552885 CCRIS 3629 F6R2N217HS Growth hormone-release inhibiting factor: L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine cyclic (3->14) disulfide NCGC00167137-01 Somatostatin [BAN:INN] Somatostatine [INN-French] Synthetic somatostatin-14 52769-04-7 BDBM81767 CHEMBL1823872 [ Show all ]
Inchi Key	NHXLMOGPVYXJNR-ATOGVRKGSA-N
Inchi ID	InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1
PubChem CID	16129706
ChEMBL	CHEMBL1823872
IUPHAR	N/A
BindingDB	81767
DrugBank	DB09099
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
223713	Delta-type opioid receptor	P33533	Oprd1	Rattus norvegicus (Rat)	372
223714	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398
223704	Somatostatin receptor type 1	P30872	SSTR1	Homo sapiens (Human)	391
223715	Somatostatin receptor type 1	P28646	Sstr1	Rattus norvegicus (Rat)	391
223705	Somatostatin receptor type 2	P30875	Sstr2	Mus musculus (Mouse)	369
223709	Somatostatin receptor type 2	P30874	SSTR2	Homo sapiens (Human)	369
556353	Somatostatin receptor type 2	P30680	Sstr2	Rattus norvegicus (Rat)	369
223707	Somatostatin receptor type 3	P32745	SSTR3	Homo sapiens (Human)	418
223708	Somatostatin receptor type 3	P30935	Sstr3	Mus musculus (Mouse)	428
223712	Somatostatin receptor type 3	P30936	Sstr3	Rattus norvegicus (Rat)	428
223706	Somatostatin receptor type 4	P31391	SSTR4	Homo sapiens (Human)	388
223710	Somatostatin receptor type 4	P30937	Sstr4	Rattus norvegicus (Rat)	384
461168	Somatostatin receptor type 4	P49660	Sstr4	Mus musculus (Mouse)	385
223703	Somatostatin receptor type 5	P35346	SSTR5	Homo sapiens (Human)	364
223711	Somatostatin receptor type 5	P30938	Sstr5	Rattus norvegicus (Rat)	363

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