You can:
| Name | Muscarinic acetylcholine receptor M5 |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Chrm5 |
| Synonym | cholinergic receptor cholinergic receptor, muscarinic 5 M5 receptor M5R |
| Disease | N/A for non-human GPCRs |
| Length | 531 |
| Amino acid sequence | MEGESYNESTVNGTPVNHQALERHGLWEVITIAVVTAVVSLMTIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWVLGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLVSFILWAPAILCWQYLVGKRTVPPDECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVAEAKKREPAQRTLLRSFFSCPRPSLAQRERNQASWSSSRRSTSTTGKTTQATDLSADWEKAEQVTTCSSYPSSEDEAKPTTDPVFQMVYKSEAKESPGKESNTQETKETVVNTRTENSDYDTPKYFLSPAAAHRLKSQKCVAYKFRLVVKADGTQETNNGCRKVKIMPCSFPVSKDPSTKGPDPNLSHQMTKRKRMVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLGYWLCYVNSTINPICYALCNRTFRKTFKLLLLCRWKKKKVEEKLYWQGNSKLP |
| UniProt | P08911 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL277 |
| IUPHAR | 17 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 8307 |  CHEMBL6747 | C20H24N2 | 292.426 | 2 / 0 | 3.5 | Yes |
| 20187 |  imipramine | C19H24N2 | 280.415 | 2 / 0 | 4.8 | Yes |
| 21404 |  CHEMBL68240 | C12H15NO2 | 205.257 | 3 / 1 | 1.2 | Yes |
| 25717 |  CHEMBL6482 | C22H28N2 | 320.48 | 2 / 0 | 4.3 | Yes |
| 37696 |  CHEMBL1916225 | C21H30FN3O3 | 391.487 | 5 / 1 | 3.1 | Yes |
| 38767 |  CHEMBL1459098 | C23H17FN2O2 | 372.399 | 3 / 0 | 3.6 | Yes |
| 44160 |  VU 0238429 | C17H12F3NO4 | 351.281 | 7 / 0 | 3.5 | Yes |
| 45152 |  CHEMBL445106 | C12H14BrNO2 | 284.153 | 3 / 1 | 1.9 | Yes |
| 45940 |  CHEMBL1916228 | C21H31N3O4 | 389.496 | 5 / 1 | 2.6 | Yes |
| 52296 |  TBPB | C25H32N4O | 404.558 | 3 / 1 | 4.4 | Yes |
| 68968 |  CHEMBL6575 | C19H20N4O4 | 368.393 | 6 / 0 | 2.7 | Yes |
| 76776 |  CHEMBL6446 | C20H24N2O | 308.425 | 3 / 0 | 3.1 | Yes |
| 444853 |  CHEMBL3329755 | C23H25F3N4O3S | 494.533 | 8 / 1 | 3.4 | Yes |
| 103509 |  CHEMBL2315680 | C20H27F3N4O3 | 428.456 | 8 / 1 | 2.5 | Yes |
| 107432 |  ml375 | C23H15ClF2N2O2 | 424.832 | 4 / 0 | 4.3 | Yes |
| 107443 |  CHEMBL3105213 | C23H15ClF2N2O2 | 424.832 | 4 / 0 | 4.3 | Yes |
| 108098 |  CHEMBL2312346 | C23H27NO4 | 381.472 | 5 / 0 | 3.6 | Yes |
| 108412 |  CHEMBL6574 | C25H26N2 | 354.497 | 2 / 0 | 4.6 | Yes |
| 122971 |  CHEMBL6603 | C18H22N2 | 266.388 | 2 / 2 | 2.7 | Yes |
| 553927 |  4-Diphenylacetoxy-1,1-dimethylpiperidinium | C21H26NO2+ | 324.444 | 2 / 0 | 4.0 | Yes |
| 133383 |  CHEMBL404874 | C18H28ClN3O | 337.892 | 3 / 1 | 3.7 | Yes |
| 134882 |  CHEMBL1916229 | C20H27F2N3O3 | 395.451 | 6 / 1 | 2.8 | Yes |
| 135533 |  CHEMBL271704 | C22H26ClN3O | 383.92 | 3 / 1 | 3.9 | Yes |
| 142578 |  CHEMBL6445 | C18H20N2 | 264.372 | 2 / 1 | 2.6 | Yes |
| 143611 |  CHEMBL255523 | C20H30ClN3O | 363.93 | 3 / 1 | 4.5 | Yes |
| 144357 |  CHEMBL6638 | C24H32N2 | 348.534 | 2 / 0 | 5.4 | No |
| 153068 |  CHEMBL1916230 | C21H31N3O3 | 373.497 | 4 / 1 | 3.0 | Yes |
| 482045 |  ML381 | C21H21N3O4 | 379.416 | 6 / 0 | 2.2 | Yes |
| 482046 |  MLS001101196 | C21H21N3O4 | 379.416 | 6 / 0 | 2.2 | Yes |
| 161470 |  CHEMBL6627 | C19H22N2 | 278.399 | 2 / 0 | 3.1 | Yes |
| 167411 |  CHEMBL414182 | C18H22N2 | 266.388 | 2 / 1 | 2.9 | Yes |
| 173790 |  CHEMBL540195 | C19H22N2O | 294.398 | 3 / 1 | 2.7 | Yes |
| 540457 |  CHEMBL3963788 | C17H16F2N4O3S2 | 426.457 | 9 / 2 | 3.1 | Yes |
| 195457 |  CHEMBL2381694 | C17H12F3NO4 | 351.281 | 7 / 0 | 3.7 | Yes |
| 449559 |  CHEMBL3353277 | C25H19F3N2O3 | 452.433 | 6 / 0 | 4.1 | Yes |
| 449561 |  CHEMBL3353290 | C25H19F3N2O3 | 452.433 | 6 / 0 | 4.1 | Yes |
| 212115 |  CHEMBL6455 | C19H23N3 | 293.414 | 3 / 1 | 2.4 | Yes |
| 229496 |  CHEMBL1916232 | C18H27N3O3S | 365.492 | 5 / 1 | 2.6 | Yes |
| 230357 |  CHEMBL66241 | C14H19NO2 | 233.311 | 3 / 0 | 2.2 | Yes |
| 231902 |  CHEMBL1916235 | C19H33N3O3 | 351.491 | 4 / 1 | 2.5 | Yes |
| 234076 |  CHEMBL1916231 | C20H35N3O3 | 365.518 | 4 / 1 | 3.0 | Yes |
| 234892 |  CHEMBL1916224 | C21H31N3O3 | 373.497 | 4 / 1 | 3.0 | Yes |
| 253715 |  CHEMBL1916227 | C20H28FN3O3 | 377.46 | 5 / 1 | 2.7 | Yes |
| 261635 |  CHEMBL1916233 | C21H31N3O4 | 389.496 | 5 / 1 | 2.6 | Yes |
| 495363 |  CHEMBL3186979 | C21H22N4O3 | 378.432 | 6 / 1 | 2.2 | Yes |
| 543190 |  CHEMBL3942511 | C16H15F5N4OS2 | 438.435 | 10 / 2 | 6.2 | No |
| 269077 |  CHEMBL271519 | C19H22ClN3O | 343.855 | 3 / 1 | 4.1 | Yes |
| 285301 |  CHEMBL2315676 | C27H34N4O | 430.596 | 3 / 1 | 4.1 | Yes |
| 285567 |  CHEMBL1916226 | C20H29N3O3 | 359.47 | 4 / 1 | 2.6 | Yes |
| 554691 |  hexahydrosiladifenidol | C20H33NOSi | 331.575 | 2 / 1 | N/A | N/A |
| 498775 |  CHEMBL3186239 | C22H23N3O4 | 393.443 | 6 / 0 | 2.6 | Yes |
| 293667 |  CHEMBL3105208 | C23H16F2N2O2 | 390.39 | 4 / 0 | 3.7 | Yes |
| 298041 |  CHEMBL6528 | C19H24N2 | 280.415 | 2 / 0 | 3.3 | Yes |
| 298612 |  L-Hyoscyamine | C17H23NO3 | 289.375 | 4 / 1 | 1.8 | Yes |
| 554752 |  pirenzepine | C19H21N5O2 | 351.41 | 5 / 1 | 0.1 | Yes |
| 301477 |  CHEMBL404992 | C21H26N2 | 306.453 | 2 / 0 | 4.0 | Yes |
| 302408 |  abt-702 | C22H19BrN6O | 463.339 | 7 / 1 | 3.4 | Yes |
| 311514 |  CHEMBL255169 | C21H26ClN3O | 371.909 | 3 / 1 | 3.9 | Yes |
| 318951 |  BAS 07465564 | C20H24ClN3O2 | 373.881 | 4 / 1 | 3.7 | Yes |
| 319616 |  CHEMBL258335 | C21H26ClN3O2 | 387.908 | 4 / 1 | 3.4 | Yes |
| 554927 |  Otenzepad | C24H31N5O2 | 421.545 | 5 / 1 | 2.0 | Yes |
| 545013 |  VU0467154 | C17H15F3N4O3S2 | 444.447 | 10 / 2 | 3.4 | Yes |
| 335056 |  mianserin | C18H20N2 | 264.372 | 2 / 0 | 3.4 | Yes |
| 339590 |  CHEMBL258281 | C16H24ClN3O | 309.838 | 3 / 1 | 3.4 | Yes |
| 346694 |  CHEMBL2315675 | C25H31FN4O | 422.548 | 4 / 1 | 3.8 | Yes |
| 348673 |  CHEMBL6649 | C17H20N2 | 252.361 | 2 / 2 | 2.4 | Yes |
| 352437 |  CHEMBL266801 | C19H21N3O2 | 323.396 | 4 / 0 | 2.9 | Yes |
| 356317 |  CHEMBL2313377 | C13H14ClN3OS | 295.785 | 4 / 2 | 3.6 | Yes |
| 363516 |  CHEMBL1916234 | C20H28ClN3O3 | 393.912 | 4 / 1 | 3.2 | Yes |
| 378659 |  D07DEY | C13H18N2O | 218.3 | 2 / 2 | 0.8 | Yes |
| 390386 |  CHEMBL429320 | C19H28ClN3O | 349.903 | 3 / 1 | 4.4 | Yes |
| 396179 |  CHEMBL2057417 | C16H15ClN4OS | 346.833 | 5 / 2 | 3.5 | Yes |
| 414748 |  CHEBI:31843 | C18H21ClN2 | 300.83 | 3 / 1 | N/A | N/A |
| 422705 |  CHEMBL256202 | C18H28ClN3O | 337.892 | 3 / 1 | 3.9 | Yes |
| 424595 |  CHEMBL1624037 | C18H27N3O3 | 333.432 | 4 / 2 | 2.0 | Yes |
| 425169 |  CHEMBL6459 | C19H21ClN2 | 312.841 | 2 / 0 | 3.7 | Yes |
| 427702 |  CHEMBL438706 | C20H23ClFN3O | 375.872 | 4 / 1 | 3.7 | Yes |
| 437113 |  CHEMBL266039 | C26H28N2 | 368.524 | 2 / 0 | 5.0 | Yes |
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