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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1459098
Molecular formula	C23H17FN2O2
IUPAC name	1-(4-fluorobenzoyl)-9b-phenyl-2,3-dihydroimidazo[2,1-a]isoindol-5-one
Molecular weight	372.399
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.6
Synonyms	1-(4-fluorobenzoyl)-9b-phenyl-1H,2H,3H,5H,9bH-imidazo[2,1-a]isoindol-5-one AKOS001026583 KS-0000365U VU0352221-2 327979-63-5 Bionet1_002747 MolPort-002-563-236 1-(4-Fluoro-benzoyl)-9b-phenyl-1,2,3,9b-tetrahydro-imidazo[2,1-a]isoindol-5-one AB00106294-01 HMS2800F10 SMR000427625 1-(4-fluorobenzoyl)-9b-phenyl-2,3-dihydroimidazo[2,1-a]isoindol-5-one AKOS016340004 MCULE-6596610047 VU0352221-3 3M-501S Oprea1_169815 1-(4-fluorobenzoyl)-9b-phenyl-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-one AC1NQ3O1 HMS576F09 STK837602 1-[(4-fluorophenyl)carbonyl]-9b-phenyl-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-one BDBM50445225 MLS001049253 SCHEMBL1247416 [ Show all ]
Inchi Key	CCNNNCNYEOXXMF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H17FN2O2/c24-18-12-10-16(11-13-18)21(27)25-14-15-26-22(28)19-8-4-5-9-20(19)23(25,26)17-6-2-1-3-7-17/h1-13H,14-15H2
PubChem CID	5189681
ChEMBL	CHEMBL1459098
IUPHAR	N/A
BindingDB	50445225
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
38768	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
38766	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
38770	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
38769	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479
38767	Muscarinic acetylcholine receptor M5	P08911	Chrm5	Rattus norvegicus (Rat)	531
38771	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532

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