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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2313377
Molecular formula	C13H14ClN3OS
IUPAC name	3-amino-5-chloro-N-cyclopropyl-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide
Molecular weight	295.785
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.6
Synonyms	VU0449033-3 N-Cyclopropyl-3-amino-4,6-dimethyl-5-chlorothieno[2,3-b]pyridine-2-carboxamide SMR002528243 BDBM50423968 MLS003871705
Inchi Key	VIZLOCIWSKXQJN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H14ClN3OS/c1-5-8-10(15)11(12(18)17-7-3-4-7)19-13(8)16-6(2)9(5)14/h7H,3-4,15H2,1-2H3,(H,17,18)
PubChem CID	53382542
ChEMBL	CHEMBL2313377
IUPHAR	N/A
BindingDB	50423968
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
356319	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
356320	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
356315	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
356316	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
356321	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
356322	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589
356313	Muscarinic acetylcholine receptor M4	P08485	Chrm4	Rattus norvegicus (Rat)	478
356314	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479
356317	Muscarinic acetylcholine receptor M5	P08911	Chrm5	Rattus norvegicus (Rat)	531
356318	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532

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