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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3353290
Molecular formula	C25H19F3N2O3
IUPAC name	(9bS)-9b-(4-methoxy-3-methylphenyl)-1-(3,4,5-trifluorobenzoyl)-2,3-dihydroimidazo[2,1-a]isoindol-5-one
Molecular weight	452.433
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	4.1
Synonyms	BDBM50042441
Inchi Key	LYXGACOPHGGKEX-VWLOTQADSA-N
Inchi ID	InChI=1S/C25H19F3N2O3/c1-14-11-16(7-8-21(14)33-2)25-18-6-4-3-5-17(18)24(32)30(25)10-9-29(25)23(31)15-12-19(26)22(28)20(27)13-15/h3-8,11-13H,9-10H2,1-2H3/t25-/m0/s1
PubChem CID	118719502
ChEMBL	CHEMBL3353290
IUPHAR	N/A
BindingDB	50042441
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
449560	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532
449561	Muscarinic acetylcholine receptor M5	P08911	Chrm5	Rattus norvegicus (Rat)	531

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