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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL445106
Molecular formula	C12H14BrNO2
IUPAC name	(4S,6R)-11-bromo-9-methoxy-2-oxatricyclo[6.3.1.04,12]dodeca-1(11),8(12),9-trien-6-amine
Molecular weight	284.153
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	1.9
Synonyms	BDBM50064706 (2aS)-6-Methoxy-8-bromo-2aalpha,3,4,5-tetrahydro-2H-naphtho[1,8-bc]furan-4beta-amine 8-Bromo-6-methoxy-2a,3,4,5-tetrahydro-2H-naphtho[1,8-bc]furan-4-ylamine (2aS,4R)-8-Bromo-6-methoxy-2a,3,4,5-tetrahydro-2H-naphtho[1,8-bc]furan-4-ylamine
Inchi Key	CLZKGXPLDDUCQZ-RNFRBKRXSA-N
Inchi ID	InChI=1S/C12H14BrNO2/c1-15-10-4-9(13)12-11-6(5-16-12)2-7(14)3-8(10)11/h4,6-7H,2-3,5,14H2,1H3/t6-,7-/m1/s1
PubChem CID	10085260
ChEMBL	CHEMBL445106
IUPHAR	N/A
BindingDB	50064706
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
45148	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
45142	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
45144	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
45150	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
45143	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
45145	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
45146	Muscarinic acetylcholine receptor M1	P12657	Chrm1	Mus musculus (Mouse)	460
45151	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
45147	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589
45149	Muscarinic acetylcholine receptor M4	P08485	Chrm4	Rattus norvegicus (Rat)	478
45152	Muscarinic acetylcholine receptor M5	P08911	Chrm5	Rattus norvegicus (Rat)	531

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