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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	ML381
Molecular formula	C21H21N3O4
IUPAC name	5-[(3-acetylphenoxy)methyl]-N-methyl-N-[(1S)-1-pyridin-2-ylethyl]-1,2-oxazole-3-carboxamide
Molecular weight	379.416
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	2.2
Synonyms	5-[(3-acetylphenoxy)methyl]-N-methyl-N-[(1S)-1-pyridin-2-ylethyl]-1,2-oxazole-3-carboxamide CHEMBL3185781 D00WNA VU0488130-1 GTPL8591
Inchi Key	JMYDHMCYZKRDPD-AWEZNQCLSA-N
Inchi ID	InChI=1S/C21H21N3O4/c1-14(19-9-4-5-10-22-19)24(3)21(26)20-12-18(28-23-20)13-27-17-8-6-7-16(11-17)15(2)25/h4-12,14H,13H2,1-3H3/t14-/m0/s1
PubChem CID	42519285
ChEMBL	CHEMBL3185781
IUPHAR	8591
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
554039	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
554038	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
554040	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
554041	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479
154834	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532
482045	Muscarinic acetylcholine receptor M5	P08911	Chrm5	Rattus norvegicus (Rat)	531

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