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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL258281
Molecular formula	C16H24ClN3O
IUPAC name	N-[3-chloro-4-(4-ethylpiperazin-1-yl)phenyl]butanamide
Molecular weight	309.838
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.4
Synonyms	N-[3-chloro-4-(4-ethylpiperazin-1-yl)phenyl]butanamide BAS 08836058 N-[3-chloro-4-(4-ethyl-1-piperazinyl)phenyl]butanamide AG-670/42683294 BDBM50373840 STK132741 MCULE-3953349217 672935-54-5 N-[3-Chloro-4-(4-ethyl-piperazin-1-yl)-phenyl]-butyramide AKOS000452683 ZINC813635 MolPort-000-751-715 AC1LD9DJ [ Show all ]
Inchi Key	ULLDFBZUOXJYID-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H24ClN3O/c1-3-5-16(21)18-13-6-7-15(14(17)12-13)20-10-8-19(4-2)9-11-20/h6-7,12H,3-5,8-11H2,1-2H3,(H,18,21)
PubChem CID	644499
ChEMBL	CHEMBL258281
IUPHAR	N/A
BindingDB	50373840
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
339588	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
339587	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
339591	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589
339589	Muscarinic acetylcholine receptor M4	P08485	Chrm4	Rattus norvegicus (Rat)	478
339590	Muscarinic acetylcholine receptor M5	P08911	Chrm5	Rattus norvegicus (Rat)	531

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