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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3942511
Molecular formula	C16H15F5N4OS2
IUPAC name	5-amino-3,4-dimethyl-N-[[4-(pentafluoro-lambda6-sulfanyl)phenyl]methyl]thieno[2,3-c]pyridazine-6-carboxamide
Molecular weight	438.435
Hydrogen bond acceptor	10
Hydrogen bond donor	2
XlogP	6.2
Synonyms	BDBM50207516 PSCQDXGBEMJRFR-UHFFFAOYSA-N 5-amino-N-(4-(pentafluorosulfanyl)benzyl)-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide SCHEMBL15212236
Inchi Key	PSCQDXGBEMJRFR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H15F5N4OS2/c1-8-9(2)24-25-16-12(8)13(22)14(27-16)15(26)23-7-10-3-5-11(6-4-10)28(17,18,19,20)21/h3-6H,7,22H2,1-2H3,(H,23,26)
PubChem CID	89768546
ChEMBL	CHEMBL3942511
IUPHAR	N/A
BindingDB	50207516
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
543185	Growth hormone secretagogue receptor type 1	Q92847	GHSR	Homo sapiens (Human)	366
543181	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
543187	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
543182	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
543184	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
543186	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589
543188	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
543180	Muscarinic acetylcholine receptor M4	P08485	Chrm4	Rattus norvegicus (Rat)	478
543183	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479
543189	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532
543190	Muscarinic acetylcholine receptor M5	P08911	Chrm5	Rattus norvegicus (Rat)	531

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