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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1916224
Molecular formula	C21H31N3O3
IUPAC name	ethyl 4-[(3R)-3-[(2-methylbenzoyl)amino]piperidin-1-yl]piperidine-1-carboxylate
Molecular weight	373.497
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.0
Synonyms	NCGC00402271-03 ZINC68245534 (R)-ethyl 3-(2-methylbenzamido)-1,4'-bipiperidine-1'-carboxylate NYDGEZQQIMDHCY-QGZVFWFLSA-N SCHEMBL1618637 BDBM50356966 [ Show all ]
Inchi Key	NYDGEZQQIMDHCY-QGZVFWFLSA-N
Inchi ID	InChI=1S/C21H31N3O3/c1-3-27-21(26)23-13-10-18(11-14-23)24-12-6-8-17(15-24)22-20(25)19-9-5-4-7-16(19)2/h4-5,7,9,17-18H,3,6,8,10-15H2,1-2H3,(H,22,25)/t17-/m1/s1
PubChem CID	57391102
ChEMBL	CHEMBL1916224
IUPHAR	N/A
BindingDB	50356966
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
234893	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
234886	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
234887	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
234888	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
234894	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
234885	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589
234890	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
234889	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479
234891	Muscarinic acetylcholine receptor M4	P08485	Chrm4	Rattus norvegicus (Rat)	478
234892	Muscarinic acetylcholine receptor M5	P08911	Chrm5	Rattus norvegicus (Rat)	531
234895	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532

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