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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1916229
Molecular formula	C20H27F2N3O3
IUPAC name	ethyl 4-[(3R)-3-[(3,4-difluorobenzoyl)amino]piperidin-1-yl]piperidine-1-carboxylate
Molecular weight	395.451
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.8
Synonyms	SCHEMBL1619885 BDBM50356974 IJQXDFSCRFNWAM-OAHLLOKOSA-N (R)-ethyl 3-(3,4-difluorobezamido)-1,4'-bipiperidine-1'-carboxylate
Inchi Key	IJQXDFSCRFNWAM-OAHLLOKOSA-N
Inchi ID	InChI=1S/C20H27F2N3O3/c1-2-28-20(27)24-10-7-16(8-11-24)25-9-3-4-15(13-25)23-19(26)14-5-6-17(21)18(22)12-14/h5-6,12,15-16H,2-4,7-11,13H2,1H3,(H,23,26)/t15-/m1/s1
PubChem CID	57394608
ChEMBL	CHEMBL1916229
IUPHAR	N/A
BindingDB	50356974
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
134884	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
134885	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
134886	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589
134883	Muscarinic acetylcholine receptor M4	P08485	Chrm4	Rattus norvegicus (Rat)	478
134882	Muscarinic acetylcholine receptor M5	P08911	Chrm5	Rattus norvegicus (Rat)	531

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