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| Name | Glucagon-like peptide 2 receptor |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | GLP2R |
| Synonym | GLP-2R GLP-2-R GLP-2 receptor |
| Disease | Diarrhea Gastrointestinal disease Short bowel syndrome Osteoporosis Inflammatory bowel disease |
| Length | 553 |
| Amino acid sequence | MKLGSSRAGPGRGSAGLLPGVHELPMGIPAPWGTSPLSFHRKCSLWAPGRPFLTLVLLVSIKQVTGSLLEETTRKWAQYKQACLRDLLKEPSGIFCNGTFDQYVCWPHSSPGNVSVPCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDDSECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMSTSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVPWGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKYRLAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKYWVRFLLARHSGCRACVLGKDFRFLGKCPKKLSEGDGAEKLRKLQPSLNSGRLLHLAMRGLGELGAQPQQDHARWPRGSSLSECSEGDVTMANTMEEILEESEI |
| UniProt | O95838 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | T34843 |
| ChEMBL | CHEMBL5844 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 521624 |  CHEMBL3824232 | C175H261N43O52 | 3799.26 | 56 / 53 | -8.9 | No |
| 521706 |  CHEMBL3822888 | C158H240N40O46 | 3435.89 | 50 / 48 | -8.2 | No |
| 11173 |  CHEMBL2178042 | C14H13Cl2NOS2 | 346.284 | 4 / 1 | 6.4 | No |
| 521862 |  CHEMBL3823043 | C172H262ClN43O52 | 3799.69 | 56 / 53 | -8.5 | No |
| 14381 |  CHEMBL2177998 | C19H22BrNO2S | 408.354 | 4 / 1 | 6.4 | No |
| 521920 |  CHEMBL3823541 | C172H263N43O52 | 3765.25 | 56 / 53 | -9.1 | No |
| 19062 |  CHEMBL2178034 | C12H8Cl2FNOS2 | 336.22 | 5 / 1 | 5.8 | No |
| 19987 |  CHEMBL2178044 | C13H10Cl2FNOS2 | 350.247 | 5 / 1 | 6.2 | No |
| 557926 |  CHEMBL2177114 | C17H18F3N3OS | 369.406 | 7 / 1 | 4.8 | Yes |
| 558263 |  CHEMBL2178005 | C15H16F3N3OS | 343.368 | 7 / 1 | 4.4 | Yes |
| 37133 |  CHEMBL2178045 | C14H13Cl2NO2S2 | 362.283 | 5 / 1 | 6.0 | No |
| 522752 |  CHEMBL3822928 | C186H289N45O58 | 4083.61 | 62 / 55 | -10.3 | No |
| 522792 |  TEDUGLUTIDE RECOMBINANT | C164H252N44O55S | 3752.13 | 60 / 55 | -15.2 | No |
| 522842 |  CHEMBL3823722 | C161H238N40O46 | 3469.91 | 50 / 48 | -7.9 | No |
| 49108 |  CHEMBL2178046 | C12H10Cl2N2OS2 | 333.245 | 5 / 1 | 5.0 | Yes |
| 523033 |  CHEMBL3823133 | C172H262N42O53 | 3766.23 | 57 / 53 | -8.5 | No |
| 55444 |  CHEMBL2177991 | C16H11F6NOS | 379.32 | 9 / 1 | 5.9 | No |
| 60497 |  CHEMBL2178014 | C13H11Cl2NO2S2 | 348.256 | 5 / 1 | 5.7 | No |
| 523391 |  CHEMBL3822726 | C151H232N42O48 | 3403.76 | 52 / 50 | -14.2 | No |
| 523393 |  CHEMBL3824274 | C151H232N42O48 | 3403.76 | 52 / 50 | -14.2 | No |
| 523396 |  CHEMBL3822834 | C151H232N42O48 | 3403.76 | 52 / 50 | -14.2 | No |
| 523398 |  CHEMBL3823370 | C151H232N42O48 | 3403.76 | 52 / 50 | -14.2 | No |
| 523399 |  CHEMBL3823635 | C151H232N42O48 | 3403.76 | 52 / 50 | -14.2 | No |
| 523402 |  CHEMBL3824343 | C151H232N42O48 | 3403.76 | 52 / 50 | -14.2 | No |
| 523403 |  CHEMBL3823156 | C151H232N42O48 | 3403.76 | 52 / 50 | -14.2 | No |
| 523405 |  CHEMBL3822879 | C151H232N42O48 | 3403.76 | 52 / 50 | -14.2 | No |
| 523407 |  CHEMBL3823589 | C151H232N42O48 | 3403.76 | 52 / 50 | -14.2 | No |
| 523409 |  CHEMBL3823217 | C151H232N42O48 | 3403.76 | 52 / 50 | -14.2 | No |
| 523412 |  CHEMBL3822814 | C151H232N42O48 | 3403.76 | 52 / 50 | -14.2 | No |
| 523414 |  CHEMBL3822971 | C151H232N42O48 | 3403.76 | 52 / 50 | -14.2 | No |
| 523415 |  CHEMBL3823106 | C151H232N42O48 | 3403.76 | 52 / 50 | -14.2 | No |
| 523417 |  CHEMBL3822747 | C151H232N42O48 | 3403.76 | 52 / 50 | -14.2 | No |
| 523419 |  CHEMBL3822745 | C151H232N42O48 | 3403.76 | 52 / 50 | -14.2 | No |
| 523421 |  CHEMBL3822778 | C151H232N42O48 | 3403.76 | 52 / 50 | -14.2 | No |
| 523424 |  CHEMBL3823662 | C151H232N42O48 | 3403.76 | 52 / 50 | -14.2 | No |
| 523425 |  CHEMBL3823175 | C151H232N42O48 | 3403.76 | 52 / 50 | -14.2 | No |
| 523427 |  CHEMBL3823545 | C151H232N42O48 | 3403.76 | 52 / 50 | -14.2 | No |
| 559307 |  CHEMBL2178007 | C17H20F3N3OS | 371.422 | 7 / 1 | 5.4 | No |
| 523663 |  CHEMBL3823847 | C171H263N43O53S | 3801.29 | 58 / 54 | -10.0 | No |
| 523872 |  CHEMBL3822625 | C162H239N41O47 | 3512.93 | 51 / 49 | -9.4 | No |
| 523995 |  CHEMBL3823643 | C156H235N41O47 | 3436.84 | 51 / 49 | -11.1 | No |
| 560214 |  CHEMBL2178006 | C16H18F3N3OS | 357.395 | 7 / 1 | 4.9 | Yes |
| 94433 |  CHEMBL2178041 | C14H13Cl2NOS2 | 346.284 | 4 / 1 | 6.4 | No |
| 99381 |  CHEMBL2177989 | C20H21BrF3NO2S | 476.352 | 7 / 1 | 7.3 | No |
| 560443 |  CHEMBL2178003 | C13H12F3N3OS | 315.314 | 7 / 1 | 3.7 | Yes |
| 524472 |  CHEMBL3822459 | C175H260N42O53 | 3800.25 | 57 / 53 | -8.2 | No |
| 524513 |  CHEMBL3823334 | C159H236N40O47S | 3491.93 | 52 / 49 | -8.6 | No |
| 524522 |  CHEMBL3823126 | C157H237N41O47 | 3450.86 | 51 / 49 | -10.7 | No |
| 524624 |  CHEMBL3824332 | C175H260ClN43O52 | 3833.7 | 56 / 53 | -8.2 | No |
| 524839 |  CHEMBL3823225 | C152H234N42O48 | 3417.79 | 52 / 50 | -13.8 | No |
| 116175 |  CHEMBL2178054 | C17H19NO2S | 301.404 | 4 / 1 | 5.0 | Yes |
| 127487 |  CHEMBL2178052 | C15H12N2OS | 268.334 | 4 / 1 | 3.8 | Yes |
| 525311 |  CHEMBL3823082 | C153H233N43O47 | 3426.8 | 52 / 50 | -12.9 | No |
| 137611 |  CHEMBL2178030 | C16H17Cl2NOS2 | 374.338 | 4 / 1 | 7.4 | No |
| 144223 |  CHEMBL2178049 | C17H12Cl2N2OS2 | 395.316 | 5 / 1 | 6.3 | No |
| 525682 |  CHEMBL3822701 | C156H241N41O47 | 3442.88 | 51 / 49 | -9.9 | No |
| 525842 |  CHEMBL3823878 | C153H237N41O47 | 3402.82 | 51 / 49 | -11.3 | No |
| 525879 |  CHEMBL3823448 | C156H234ClN41O47 | 3471.28 | 51 / 49 | -10.4 | No |
| 525892 |  CHEMBL3824159 | C158H236N42O47 | 3475.87 | 51 / 50 | -10.9 | No |
| 525894 |  CHEMBL3822981 | C158H236N42O47 | 3475.87 | 51 / 50 | -10.9 | No |
| 158181 |  CHEMBL2178013 | C13H11Cl2NO2S2 | 348.256 | 5 / 1 | 5.7 | No |
| 526074 |  CHEMBL3823053 | C153H237N41O47 | 3402.82 | 51 / 49 | -11.3 | No |
| 526075 |  CHEMBL3823333 | C153H237N41O47 | 3402.82 | 51 / 49 | -11.3 | No |
| 526256 |  CHEMBL3823976 | C183H284N44O57 | 4012.54 | 61 / 54 | -10.5 | No |
| 169310 |  CHEMBL2178020 | C16H11Cl2NOS2 | 368.29 | 4 / 1 | 7.0 | No |
| 174638 |  CHEMBL2177993 | C22H29NOS | 355.54 | 3 / 1 | 7.4 | No |
| 526536 |  CHEMBL3823411 | C156H234ClN41O47 | 3471.28 | 51 / 49 | -10.4 | No |
| 526553 |  CHEMBL3823985 | C176H271N43O52 | 3821.35 | 56 / 53 | -7.4 | No |
| 526649 |  CHEMBL3822792 | C178H268N44O52 | 3856.36 | 57 / 53 | -8.3 | No |
| 185392 |  CHEMBL2178032 | C12H8Cl2FNOS2 | 336.22 | 5 / 1 | 5.8 | No |
| 186971 |  CHEMBL2177996 | C24H31NO4S | 429.575 | 6 / 1 | 6.6 | No |
| 526896 |  CHEMBL3823835 | C159H242N40O47 | 3465.92 | 51 / 49 | -8.8 | No |
| 526953 |  CHEMBL3823760 | C153H233N43O47 | 3426.8 | 52 / 50 | -12.9 | No |
| 526955 |  CHEMBL3823576 | C153H233N43O47 | 3426.8 | 52 / 50 | -12.9 | No |
| 527132 |  CHEMBL3822975 | C156H234ClN41O47 | 3471.28 | 51 / 49 | -10.4 | No |
| 209423 |  CHEMBL2178058 | C14H12BrNOS | 322.22 | 3 / 1 | 4.8 | Yes |
| 527565 |  CHEMBL3823681 | C140H211N39O45S | 3192.52 | 49 / 46 | -11.3 | No |
| 210706 |  CHEMBL2178057 | C14H12ClNOS | 277.766 | 3 / 1 | 4.7 | Yes |
| 217177 |  CID 71455345 | C156H242N40O53S | 3557.94 | 57 / 52 | -14.1 | No |
| 564209 |  CHEMBL2178002 | C18H17N3OS | 323.414 | 4 / 1 | 4.4 | Yes |
| 527858 |  CHEMBL3823889 | C154H233N41O47S | 3442.86 | 52 / 49 | -11.3 | No |
| 527977 |  CHEMBL3824241 | C156H238N40O46S | 3441.91 | 51 / 48 | -8.5 | No |
| 528095 |  CHEMBL3823144 | C179H269N43O52 | 3855.37 | 56 / 53 | -7.2 | No |
| 528181 |  CHEMBL3824278 | C154H233N41O47S | 3442.86 | 52 / 49 | -11.3 | No |
| 241144 |  CHEMBL2178037 | C12H8Cl3NOS2 | 352.672 | 4 / 1 | 6.3 | No |
| 565167 |  CHEMBL2178009 | C16H16F3N3OS | 355.379 | 7 / 1 | 4.5 | Yes |
| 528830 |  CHEMBL3823327 | C174H267N43O52 | 3793.3 | 56 / 53 | -8.4 | No |
| 529171 |  CHEMBL3824079 | C173H259N43O52S | 3805.28 | 57 / 53 | -9.2 | No |
| 529360 |  CHEMBL3822727 | C153H237N41O47 | 3402.82 | 51 / 49 | -11.3 | No |
| 278737 |  BDBM50398386 | C121H194N32O37 | 2689.07 | 40 / 38 | -9.9 | No |
| 279170 |  CHEMBL2178038 | C13H8Cl2F3NOS2 | 386.228 | 7 / 1 | 6.6 | No |
| 283295 |  CHEMBL2178031 | C18H13Cl2NOS2 | 394.328 | 4 / 1 | 7.3 | No |
| 285481 |  CHEMBL2178012 | C13H11Cl2NO2S2 | 348.256 | 5 / 1 | 5.7 | No |
| 529806 |  CHEMBL3823671 | C151H234N42O47 | 3389.78 | 52 / 50 | -15.9 | No |
| 299102 |  CHEMBL2178043 | C14H13Cl2NOS2 | 346.284 | 4 / 1 | 6.4 | No |
| 530147 |  CHEMBL3823291 | C159H236N40O46S | 3475.93 | 51 / 48 | -8.2 | No |
| 309898 |  CHEMBL2178010 | C14H11Cl2NO3S2 | 376.266 | 6 / 1 | 5.6 | No |
| 313460 |  CHEMBL2178055 | C17H19NO2S | 301.404 | 4 / 1 | 4.9 | Yes |
| 321487 |  CHEMBL2178011 | C12H9Cl2NOS2 | 318.23 | 4 / 1 | 5.7 | No |
| 530694 |  CHEMBL3824227 | C135H203N37O43S | 3064.39 | 47 / 44 | -9.9 | No |
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