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Name | Glucagon-like peptide 2 receptor |
---|---|
Species | Homo sapiens (Human) |
Gene | GLP2R |
Synonym | GLP-2R GLP-2-R GLP-2 receptor |
Disease | Diarrhea Gastrointestinal disease Short bowel syndrome Osteoporosis Inflammatory bowel disease |
Length | 553 |
Amino acid sequence | MKLGSSRAGPGRGSAGLLPGVHELPMGIPAPWGTSPLSFHRKCSLWAPGRPFLTLVLLVSIKQVTGSLLEETTRKWAQYKQACLRDLLKEPSGIFCNGTFDQYVCWPHSSPGNVSVPCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDDSECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMSTSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVPWGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKYRLAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKYWVRFLLARHSGCRACVLGKDFRFLGKCPKKLSEGDGAEKLRKLQPSLNSGRLLHLAMRGLGELGAQPQQDHARWPRGSSLSECSEGDVTMANTMEEILEESEI |
UniProt | O95838 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | T34843 |
ChEMBL | CHEMBL5844 |
IUPHAR | N/A |
DrugBank | N/A |
Name | CHEMBL2178045 |
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Molecular formula | C14H13Cl2NO2S2 |
IUPAC name | (NZ)-N-[1-(2,5-dichlorothiophen-3-yl)-2-(3-methoxy-2-methylphenyl)sulfanylethylidene]hydroxylamine |
Molecular weight | 362.283 |
Hydrogen bond acceptor | 5 |
Hydrogen bond donor | 1 |
XlogP | 6.0 |
Synonyms | N/A |
Inchi Key | CAGFLVNJNCAPFI-LICLKQGHSA-N |
Inchi ID | InChI=1S/C14H13Cl2NO2S2/c1-8-11(19-2)4-3-5-12(8)20-7-10(17-18)9-6-13(15)21-14(9)16/h3-6,18H,7H2,1-2H3/b17-10+ |
PubChem CID | 71459028 |
ChEMBL | CHEMBL2178045 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand has a partition coefficient log P greater than 5. |
Parameter | Value | Reference | Database source |
---|---|---|---|
%max | 31.0 % | PMID22944117 | ChEMBL |
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