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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Glucagon-like peptide 2 receptor
Species	Homo sapiens (Human)
Gene	GLP2R
Synonym	GLP-2R GLP-2-R GLP-2 receptor
Disease	Diarrhea Gastrointestinal disease Short bowel syndrome Osteoporosis Inflammatory bowel disease
Length	553
Amino acid sequence	MKLGSSRAGPGRGSAGLLPGVHELPMGIPAPWGTSPLSFHRKCSLWAPGRPFLTLVLLVSIKQVTGSLLEETTRKWAQYKQACLRDLLKEPSGIFCNGTFDQYVCWPHSSPGNVSVPCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDDSECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMSTSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVPWGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKYRLAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKYWVRFLLARHSGCRACVLGKDFRFLGKCPKKLSEGDGAEKLRKLQPSLNSGRLLHLAMRGLGELGAQPQQDHARWPRGSSLSECSEGDVTMANTMEEILEESEI
UniProt	O95838
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	T34843
ChEMBL	CHEMBL5844
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL2177114
Molecular formula	C17H18F3N3OS
IUPAC name	(NZ)-N-[1-[2-cyclopentyl-5-(trifluoromethyl)pyrazol-3-yl]-2-phenylsulfanylethylidene]hydroxylamine
Molecular weight	369.406
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.8
Synonyms	N/A
Inchi Key	BDJKGJROLUWNRW-HYARGMPZSA-N
Inchi ID	InChI=1S/C17H18F3N3OS/c18-17(19,20)16-10-15(23(21-16)12-6-4-5-7-12)14(22-24)11-25-13-8-2-1-3-9-13/h1-3,8-10,12,24H,4-7,11H2/b22-14+
PubChem CID	136230183
ChEMBL	CHEMBL2177114
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
%max	127.0 %	PMID22944117	ChEMBL

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