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Name | Glucagon-like peptide 2 receptor |
---|---|
Species | Homo sapiens (Human) |
Gene | GLP2R |
Synonym | GLP-2R GLP-2-R GLP-2 receptor |
Disease | Diarrhea Gastrointestinal disease Short bowel syndrome Osteoporosis Inflammatory bowel disease |
Length | 553 |
Amino acid sequence | MKLGSSRAGPGRGSAGLLPGVHELPMGIPAPWGTSPLSFHRKCSLWAPGRPFLTLVLLVSIKQVTGSLLEETTRKWAQYKQACLRDLLKEPSGIFCNGTFDQYVCWPHSSPGNVSVPCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDDSECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMSTSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVPWGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKYRLAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKYWVRFLLARHSGCRACVLGKDFRFLGKCPKKLSEGDGAEKLRKLQPSLNSGRLLHLAMRGLGELGAQPQQDHARWPRGSSLSECSEGDVTMANTMEEILEESEI |
UniProt | O95838 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | T34843 |
ChEMBL | CHEMBL5844 |
IUPHAR | N/A |
DrugBank | N/A |
Name | CHEMBL2178046 |
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Molecular formula | C12H10Cl2N2OS2 |
IUPAC name | (NZ)-N-[1-(2,5-dichlorothiophen-3-yl)-2-(3-methylpyridin-4-yl)sulfanylethylidene]hydroxylamine |
Molecular weight | 333.245 |
Hydrogen bond acceptor | 5 |
Hydrogen bond donor | 1 |
XlogP | 5.0 |
Synonyms | N/A |
Inchi Key | CRTPEYHITYIDNQ-CXUHLZMHSA-N |
Inchi ID | InChI=1S/C12H10Cl2N2OS2/c1-7-5-15-3-2-10(7)18-6-9(16-17)8-4-11(13)19-12(8)14/h2-5,17H,6H2,1H3/b16-9+ |
PubChem CID | 71462543 |
ChEMBL | CHEMBL2178046 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
%max | 44.0 % | PMID22944117 | ChEMBL |
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