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Name | Glucagon-like peptide 2 receptor |
---|---|
Species | Homo sapiens (Human) |
Gene | GLP2R |
Synonym | GLP-2R GLP-2-R GLP-2 receptor |
Disease | Diarrhea Gastrointestinal disease Short bowel syndrome Osteoporosis Inflammatory bowel disease |
Length | 553 |
Amino acid sequence | MKLGSSRAGPGRGSAGLLPGVHELPMGIPAPWGTSPLSFHRKCSLWAPGRPFLTLVLLVSIKQVTGSLLEETTRKWAQYKQACLRDLLKEPSGIFCNGTFDQYVCWPHSSPGNVSVPCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDDSECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMSTSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVPWGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKYRLAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKYWVRFLLARHSGCRACVLGKDFRFLGKCPKKLSEGDGAEKLRKLQPSLNSGRLLHLAMRGLGELGAQPQQDHARWPRGSSLSECSEGDVTMANTMEEILEESEI |
UniProt | O95838 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | T34843 |
ChEMBL | CHEMBL5844 |
IUPHAR | N/A |
DrugBank | N/A |
Name | CHEMBL2178034 |
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Molecular formula | C12H8Cl2FNOS2 |
IUPAC name | (NZ)-N-[1-(2,5-dichlorothiophen-3-yl)-2-(4-fluorophenyl)sulfanylethylidene]hydroxylamine |
Molecular weight | 336.22 |
Hydrogen bond acceptor | 5 |
Hydrogen bond donor | 1 |
XlogP | 5.8 |
Synonyms | N/A |
Inchi Key | BAPUIXSTKYEFBQ-MHWRWJLKSA-N |
Inchi ID | InChI=1S/C12H8Cl2FNOS2/c13-11-5-9(12(14)19-11)10(16-17)6-18-8-3-1-7(15)2-4-8/h1-5,17H,6H2/b16-10+ |
PubChem CID | 71450018 |
ChEMBL | CHEMBL2178034 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand has a partition coefficient log P greater than 5. |
Parameter | Value | Reference | Database source |
---|---|---|---|
%max | 134.0 % | PMID22944117 | ChEMBL |
%max | 945.0 % | PMID22944117 | ChEMBL |
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