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Name | Glucagon-like peptide 2 receptor |
---|---|
Species | Homo sapiens (Human) |
Gene | GLP2R |
Synonym | GLP-2R GLP-2-R GLP-2 receptor |
Disease | Diarrhea Gastrointestinal disease Short bowel syndrome Osteoporosis Inflammatory bowel disease |
Length | 553 |
Amino acid sequence | MKLGSSRAGPGRGSAGLLPGVHELPMGIPAPWGTSPLSFHRKCSLWAPGRPFLTLVLLVSIKQVTGSLLEETTRKWAQYKQACLRDLLKEPSGIFCNGTFDQYVCWPHSSPGNVSVPCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDDSECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMSTSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVPWGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKYRLAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKYWVRFLLARHSGCRACVLGKDFRFLGKCPKKLSEGDGAEKLRKLQPSLNSGRLLHLAMRGLGELGAQPQQDHARWPRGSSLSECSEGDVTMANTMEEILEESEI |
UniProt | O95838 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | T34843 |
ChEMBL | CHEMBL5844 |
IUPHAR | N/A |
DrugBank | N/A |
Name | CHEMBL2178030 |
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Molecular formula | C16H17Cl2NOS2 |
IUPAC name | (NZ)-N-[2-(2-tert-butylphenyl)sulfanyl-1-(2,5-dichlorothiophen-3-yl)ethylidene]hydroxylamine |
Molecular weight | 374.338 |
Hydrogen bond acceptor | 4 |
Hydrogen bond donor | 1 |
XlogP | 7.4 |
Synonyms | N/A |
Inchi Key | INUBLKWQGAISCA-XDHOZWIPSA-N |
Inchi ID | InChI=1S/C16H17Cl2NOS2/c1-16(2,3)11-6-4-5-7-13(11)21-9-12(19-20)10-8-14(17)22-15(10)18/h4-8,20H,9H2,1-3H3/b19-12+ |
PubChem CID | 71457154 |
ChEMBL | CHEMBL2178030 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand has a partition coefficient log P greater than 5. |
Parameter | Value | Reference | Database source |
---|---|---|---|
%max | 40.0 % | PMID22944117 | ChEMBL |
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