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Name | Glucagon-like peptide 2 receptor |
---|---|
Species | Homo sapiens (Human) |
Gene | GLP2R |
Synonym | GLP-2R GLP-2-R GLP-2 receptor |
Disease | Diarrhea Gastrointestinal disease Short bowel syndrome Osteoporosis Inflammatory bowel disease |
Length | 553 |
Amino acid sequence | MKLGSSRAGPGRGSAGLLPGVHELPMGIPAPWGTSPLSFHRKCSLWAPGRPFLTLVLLVSIKQVTGSLLEETTRKWAQYKQACLRDLLKEPSGIFCNGTFDQYVCWPHSSPGNVSVPCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDDSECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMSTSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVPWGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKYRLAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKYWVRFLLARHSGCRACVLGKDFRFLGKCPKKLSEGDGAEKLRKLQPSLNSGRLLHLAMRGLGELGAQPQQDHARWPRGSSLSECSEGDVTMANTMEEILEESEI |
UniProt | O95838 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | T34843 |
ChEMBL | CHEMBL5844 |
IUPHAR | N/A |
DrugBank | N/A |
Name | CHEMBL2178049 |
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Molecular formula | C17H12Cl2N2OS2 |
IUPAC name | (NZ)-N-[1-(2,5-dichlorothiophen-3-yl)-2-(3-phenylpyridin-4-yl)sulfanylethylidene]hydroxylamine |
Molecular weight | 395.316 |
Hydrogen bond acceptor | 5 |
Hydrogen bond donor | 1 |
XlogP | 6.3 |
Synonyms | N/A |
Inchi Key | IXRMDBAFPTZNIF-KGENOOAVSA-N |
Inchi ID | InChI=1S/C17H12Cl2N2OS2/c18-16-8-12(17(19)24-16)14(21-22)10-23-15-6-7-20-9-13(15)11-4-2-1-3-5-11/h1-9,22H,10H2/b21-14+ |
PubChem CID | 71459029 |
ChEMBL | CHEMBL2178049 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand has a partition coefficient log P greater than 5. |
Parameter | Value | Reference | Database source |
---|---|---|---|
%max | 102.0 % | PMID22944117 | ChEMBL |
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