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GPCR

NameNeurotensin receptor type 2
SpeciesHomo sapiens (Human)
GeneNTSR2
Synonymlevocabastine-sensitive neurotensin receptor
neurotensin receptor type 2
high-affinity levocabastine-sensitive neurotensin receptor
NT2R
NTR2
[ Show all ]
DiseaseN/A
Length410
Amino acid sequenceMETSSPRPPRPSSNPGLSLDARLGVDTRLWAKVLFTALYALIWALGAAGNALSAHVVLKARAGRAGRLRHHVLSLALAGLLLLLVGVPVELYSFVWFHYPWVFGDLGCRGYYFVHELCAYATVLSVAGLSAERCLAVCQPLRARSLLTPRRTRWLVALSWAASLGLALPMAVIMGQKHELETADGEPEPASRVCTVLVSRTALQVFIQVNVLVSFVLPLALTAFLNGVTVSHLLALCSQVPSTSTPGSSTPSRLELLSEEGLLSFIVWKKTFIQGGQVSLVRHKDVRRIRSLQRSVQVLRAIVVMYVICWLPYHARRLMYCYVPDDAWTDPLYNFYHYFYMVTNTLFYVSSAVTPLLYNAVSSSFRKLFLEAVSSLCGEHHPMKRLPPKPQSPTLMDTASGFGDPPETRT
UniProtO95665
Protein Data BankN/A
GPCR-HGmod modelO95665
3D structure modelThis predicted structure model is from GPCR-EXP O95665.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2514
IUPHAR310
DrugBankN/A

Known ligands

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Total entries: 136
Page:  / 2 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
38102D structureCHEMBL2431236C28H30N4O3470.5737 / 05.5No
258512D structureCHEMBL1766936C39H66N12O8831.03311 / 11-2.5No
323202D structureCHEMBL3086356C50H67FN8O10959.1315 / 52.9No
5482932D structureCHEMBL3951982C40H65BrN10O8893.92611 / 9-1.1No
388622D structureCHEMBL2431113C22H26N4O3394.4757 / 03.9Yes
405772D structureCHEMBL434227C39H66N12O8831.03312 / 11-1.5No
5483632D structureCHEMBL3950695C38H63BrN8O7823.87510 / 8-1.0No
5483652D structureCHEMBL3979668C38H63BrN8O7823.87510 / 8-1.0No
430262D structureCHEMBL2431125C24H28N4O2404.5146 / 04.6Yes
5484182D structureCHEMBL3899699C36H57BrN8O8809.80411 / 8-1.9No
616222D structureCHEMBL2431237C28H30N4O3470.5737 / 05.5No
5486242D structureCHEMBL3890335C34H54BrN7O7752.75210 / 7-1.2No
621122D structureCHEMBL1766945C39H66N10O8803.01911 / 9-1.4No
647002D structureCHEMBL2431110C17H22N4O2314.3896 / 11.9Yes
662002D structureCHEMBL1766929C38H64N12O8817.00611 / 11-4.0No
662022D structureCHEMBL1766932C38H64N12O8817.00611 / 11-4.0No
662072D structureCHEMBL342252C38H64N12O8817.00611 / 11-4.0No
662082D structureCHEMBL1766934C38H64N12O8817.00611 / 11-4.0No
4710912D structureneurotensin (8-13)C38H64N12O8817.00611 / 11-4.0No
662112D structureCHEMBL1766931C38H64N12O8817.00611 / 11-4.0No
662122D structureCHEMBL1766933C38H64N12O8817.00611 / 11-4.0No
662152D structureCHEMBL1766930C38H64N12O8817.00611 / 11-4.0No
681342D structureCHEMBL1172376C41H70ClN9O8852.51610 / 8N/ANo
714722D structureCHEMBL2431135C26H25FN4O2444.517 / 05.3No
720712D structureMeclinertantC32H31ClN4O5587.0737 / 25.8No
728882D structureCHEMBL1766942C39H66N12O7815.03410 / 9-2.0No
754362D structureCHEMBL132507C40H68N10O8817.04612 / 9-0.1No
885822D structureCHEMBL2431109C25H28N4O4448.5237 / 03.4Yes
933162D structureCHEMBL2431234C24H27ClN4O2438.9566 / 05.3No
4748542D structureCHEMBL3622803C38H68N8O8Si2821.1811 / 9N/ANo
975732D structureCHEMBL1766943C38H65N13O7816.02211 / 9-3.0No
994552D structureCHEMBL1766923C35H57N9O8731.89610 / 9-3.0No
999242D structureCHEMBL1766937C39H66N12O8831.03311 / 11-2.5No
1005092D structureCHEMBL2431233C24H27FN4O2422.5047 / 04.8Yes
1020782D structureCHEMBL1417160C23H27N5O2405.5027 / 03.9Yes
4775162D structureCHEMBL3622802C38H66N8O8Si791.07911 / 9N/ANo
1196392D structureCHEMBL1766944C39H66N10O8803.01911 / 9-1.4No
1199912D structureCHEMBL2431127C23H26N4O374.4885 / 04.7Yes
5395782D structureCHEMBL3942339C36H58N12O9802.93512 / 11-4.8No
5496782D structureCHEMBL3971946C36H58N12O9802.93512 / 11-4.8No
1485232D structureCHEMBL258221C38H64N8O8760.97811 / 9-2.1No
4818372D structureCHEMBL3622804C40H72N8O8Si2849.23411 / 9N/ANo
1542002D structureCHEMBL2431118C25H32N4O3436.5567 / 05.1No
1574622D structureCHEMBL336836C40H68N12O8845.0612 / 11-1.2No
4829962D structureCHEMBL3622805C39H68N10O8Si833.1211 / 10N/ANo
4833832D structureCHEMBL3622806C39H68N8O8Si805.10611 / 9N/ANo
1662182D structureCHEMBL435199C41H67N11O7826.05711 / 10-0.2No
1668502D structureCHEMBL1766939C39H66N12O8831.03311 / 11-2.5No
1729142D structureCHEMBL2431131C23H25ClN4O2424.9296 / 04.7Yes
1733142D structureCHEMBL2369509C38H64N8O8760.97811 / 8-0.8No
1740342D structureCHEMBL132409C38H64N12O8817.00612 / 11-3.7No
5541562D structureJMV458C45H73N13O9940.16111 / 111.9No
1825992D structureCHEMBL2431133C27H28N4O3456.5467 / 05.2No
1828912D structureCHEMBL2431108C24H26N4O3418.4976 / 03.4Yes
1868572D structureCHEMBL1766941C40H68N12O8845.0611 / 9-2.0No
1905002D structureCHEMBL133340C38H64N10O8788.99212 / 10-0.9No
1921622D structureCHEMBL132524C40H68N12O8845.0614 / 12-1.7No
5503222D structureCHEMBL3954824C34H54BrN11O7808.7810 / 9-3.1No
1962062D structureCHEMBL2431111C29H32N4O2468.6016 / 06.3No
1969752D structureCHEMBL270332C76H124N16O141485.9318 / 164.4No
1978352D structureCHEMBL129953C40H69N10O8+818.05411 / 9-0.4No
1983982D structureSR142948AC39H51N5O6685.8668 / 23.6No
2053872D structureCHEMBL2431132C23H26N4O4S454.5458 / 03.1Yes
4610492D structureBDBM50342239C38H66N12O8819.02211 / 10-3.7No
2099442D structureCHEMBL133798C41H71N10O8+832.08111 / 90.0No
2110342D structureCHEMBL430910C38H64N10O8788.99212 / 10-1.0No
5505442D structureCHEMBL3915284C40H65BrN10O8893.92611 / 9-1.1No
2146802D structureCHEMBL1766927C35H58N12O8774.92511 / 11-4.2No
2196252D structureCHEMBL2431235C27H27N5O4485.5448 / 05.4No
2317502D structureCHEMBL2431106C25H30N4O2418.5416 / 04.2Yes
2322492D structureCHEMBL2431140C27H27FN4O2458.5377 / 05.7No
2337132D structureCHEMBL335846C39H66N10O8803.01912 / 10-0.6No
4612402D structureCHEMBL1172376C41H70N9O8+817.0669 / 82.8No
2344772D structureCHEMBL2431138C28H30N4O3470.5737 / 05.5No
2435622D structureCHEMBL337644C39H66N10O8803.01912 / 10-0.7No
2472842D structureCHEMBL2431134C26H26N4O2426.526 / 05.2No
2498292D structureCHEMBL133850C41H70N10O8831.07312 / 90.3No
2501482D structureCHEMBL2431112C21H24N4O3380.4487 / 03.5Yes
2501562D structureCHEMBL1766825C39H66N12O8831.03311 / 10-2.3No
2508792D structureCHEMBL254770C38H64N8O8760.97811 / 8-0.9No
2510072D structureCHEMBL3099773C27H27ClN4O5522.9867 / 25.1No
2515772D structureCHEMBL132794C42H73N10O8+846.10811 / 90.3No
2561402D structureCHEMBL253527C39H66N12O8831.03311 / 11-3.6No
2563472D structureNEUROTENSINC78H121N21O201672.9523 / 21-3.7No
2568462D structureCHEMBL2431115C23H28N4O3408.5027 / 04.3Yes
2579942D structureCHEMBL1766946C39H66N8O8775.00511 / 8-0.4No
2586052D structureCHEMBL2431129C23H26N4O2390.4876 / 04.1Yes
2599322D structureCHEMBL2431122C25H30N4O3434.547 / 04.9Yes
2604342D structureCHEMBL439494C69H108N20O181505.7422 / 20-7.4No
5511742D structureCHEMBL3941970C34H54BrN9O7780.76610 / 8-2.2No
2705162D structureCHEMBL2431128C24H26N4O3418.4977 / 04.5Yes
2733652D structureCHEMBL2431232C25H30N4O2418.5416 / 05.0Yes
2799952D structureCHEMBL2431136C26H25FN4O2444.517 / 05.3No
5514112D structureCHEMBL3932989C34H54BrN9O7780.76610 / 8-2.2No
2840312D structureCHEMBL2431117C24H30N4O3422.5297 / 04.7Yes
2910262D structureCHEMBL2431231C24H28N4O2404.5146 / 04.6Yes
2919142D structureCHEMBL266230C39H66N12O8831.03311 / 11-2.5No
2991672D structureCHEMBL2431126C24H28N4O2404.5146 / 04.6Yes
3034462D structureCHEMBL2431123C25H33N5O3451.5718 / 03.8Yes
3050332D structureCHEMBL2431238C29H32N4O4500.5998 / 05.5No

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