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Name | Neurotensin receptor type 2 |
---|---|
Species | Homo sapiens (Human) |
Gene | NTSR2 |
Synonym | levocabastine-sensitive neurotensin receptor neurotensin receptor type 2 high-affinity levocabastine-sensitive neurotensin receptor NT2R NTR2 [ Show all ] |
Disease | N/A |
Length | 410 |
Amino acid sequence | METSSPRPPRPSSNPGLSLDARLGVDTRLWAKVLFTALYALIWALGAAGNALSAHVVLKARAGRAGRLRHHVLSLALAGLLLLLVGVPVELYSFVWFHYPWVFGDLGCRGYYFVHELCAYATVLSVAGLSAERCLAVCQPLRARSLLTPRRTRWLVALSWAASLGLALPMAVIMGQKHELETADGEPEPASRVCTVLVSRTALQVFIQVNVLVSFVLPLALTAFLNGVTVSHLLALCSQVPSTSTPGSSTPSRLELLSEEGLLSFIVWKKTFIQGGQVSLVRHKDVRRIRSLQRSVQVLRAIVVMYVICWLPYHARRLMYCYVPDDAWTDPLYNFYHYFYMVTNTLFYVSSAVTPLLYNAVSSSFRKLFLEAVSSLCGEHHPMKRLPPKPQSPTLMDTASGFGDPPETRT |
UniProt | O95665 |
Protein Data Bank | N/A |
GPCR-HGmod model | O95665 |
3D structure model | This predicted structure model is from GPCR-EXP O95665. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL2514 |
IUPHAR | 310 |
DrugBank | N/A |
You can:
GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
3810 | CHEMBL2431236 | C28H30N4O3 | 470.573 | 7 / 0 | 5.5 | No |
25851 | CHEMBL1766936 | C39H66N12O8 | 831.033 | 11 / 11 | -2.5 | No |
32320 | CHEMBL3086356 | C50H67FN8O10 | 959.13 | 15 / 5 | 2.9 | No |
548293 | CHEMBL3951982 | C40H65BrN10O8 | 893.926 | 11 / 9 | -1.1 | No |
38862 | CHEMBL2431113 | C22H26N4O3 | 394.475 | 7 / 0 | 3.9 | Yes |
40577 | CHEMBL434227 | C39H66N12O8 | 831.033 | 12 / 11 | -1.5 | No |
548363 | CHEMBL3950695 | C38H63BrN8O7 | 823.875 | 10 / 8 | -1.0 | No |
548365 | CHEMBL3979668 | C38H63BrN8O7 | 823.875 | 10 / 8 | -1.0 | No |
43026 | CHEMBL2431125 | C24H28N4O2 | 404.514 | 6 / 0 | 4.6 | Yes |
548418 | CHEMBL3899699 | C36H57BrN8O8 | 809.804 | 11 / 8 | -1.9 | No |
61622 | CHEMBL2431237 | C28H30N4O3 | 470.573 | 7 / 0 | 5.5 | No |
548624 | CHEMBL3890335 | C34H54BrN7O7 | 752.752 | 10 / 7 | -1.2 | No |
62112 | CHEMBL1766945 | C39H66N10O8 | 803.019 | 11 / 9 | -1.4 | No |
64700 | CHEMBL2431110 | C17H22N4O2 | 314.389 | 6 / 1 | 1.9 | Yes |
66200 | CHEMBL1766929 | C38H64N12O8 | 817.006 | 11 / 11 | -4.0 | No |
66202 | CHEMBL1766932 | C38H64N12O8 | 817.006 | 11 / 11 | -4.0 | No |
66207 | CHEMBL342252 | C38H64N12O8 | 817.006 | 11 / 11 | -4.0 | No |
66208 | CHEMBL1766934 | C38H64N12O8 | 817.006 | 11 / 11 | -4.0 | No |
471091 | neurotensin (8-13) | C38H64N12O8 | 817.006 | 11 / 11 | -4.0 | No |
66211 | CHEMBL1766931 | C38H64N12O8 | 817.006 | 11 / 11 | -4.0 | No |
66212 | CHEMBL1766933 | C38H64N12O8 | 817.006 | 11 / 11 | -4.0 | No |
66215 | CHEMBL1766930 | C38H64N12O8 | 817.006 | 11 / 11 | -4.0 | No |
68134 | CHEMBL1172376 | C41H70ClN9O8 | 852.516 | 10 / 8 | N/A | No |
71472 | CHEMBL2431135 | C26H25FN4O2 | 444.51 | 7 / 0 | 5.3 | No |
72071 | Meclinertant | C32H31ClN4O5 | 587.073 | 7 / 2 | 5.8 | No |
72888 | CHEMBL1766942 | C39H66N12O7 | 815.034 | 10 / 9 | -2.0 | No |
75436 | CHEMBL132507 | C40H68N10O8 | 817.046 | 12 / 9 | -0.1 | No |
88582 | CHEMBL2431109 | C25H28N4O4 | 448.523 | 7 / 0 | 3.4 | Yes |
93316 | CHEMBL2431234 | C24H27ClN4O2 | 438.956 | 6 / 0 | 5.3 | No |
474854 | CHEMBL3622803 | C38H68N8O8Si2 | 821.18 | 11 / 9 | N/A | No |
97573 | CHEMBL1766943 | C38H65N13O7 | 816.022 | 11 / 9 | -3.0 | No |
99455 | CHEMBL1766923 | C35H57N9O8 | 731.896 | 10 / 9 | -3.0 | No |
99924 | CHEMBL1766937 | C39H66N12O8 | 831.033 | 11 / 11 | -2.5 | No |
100509 | CHEMBL2431233 | C24H27FN4O2 | 422.504 | 7 / 0 | 4.8 | Yes |
102078 | CHEMBL1417160 | C23H27N5O2 | 405.502 | 7 / 0 | 3.9 | Yes |
477516 | CHEMBL3622802 | C38H66N8O8Si | 791.079 | 11 / 9 | N/A | No |
119639 | CHEMBL1766944 | C39H66N10O8 | 803.019 | 11 / 9 | -1.4 | No |
119991 | CHEMBL2431127 | C23H26N4O | 374.488 | 5 / 0 | 4.7 | Yes |
539578 | CHEMBL3942339 | C36H58N12O9 | 802.935 | 12 / 11 | -4.8 | No |
549678 | CHEMBL3971946 | C36H58N12O9 | 802.935 | 12 / 11 | -4.8 | No |
148523 | CHEMBL258221 | C38H64N8O8 | 760.978 | 11 / 9 | -2.1 | No |
481837 | CHEMBL3622804 | C40H72N8O8Si2 | 849.234 | 11 / 9 | N/A | No |
154200 | CHEMBL2431118 | C25H32N4O3 | 436.556 | 7 / 0 | 5.1 | No |
157462 | CHEMBL336836 | C40H68N12O8 | 845.06 | 12 / 11 | -1.2 | No |
482996 | CHEMBL3622805 | C39H68N10O8Si | 833.12 | 11 / 10 | N/A | No |
483383 | CHEMBL3622806 | C39H68N8O8Si | 805.106 | 11 / 9 | N/A | No |
166218 | CHEMBL435199 | C41H67N11O7 | 826.057 | 11 / 10 | -0.2 | No |
166850 | CHEMBL1766939 | C39H66N12O8 | 831.033 | 11 / 11 | -2.5 | No |
172914 | CHEMBL2431131 | C23H25ClN4O2 | 424.929 | 6 / 0 | 4.7 | Yes |
173314 | CHEMBL2369509 | C38H64N8O8 | 760.978 | 11 / 8 | -0.8 | No |
174034 | CHEMBL132409 | C38H64N12O8 | 817.006 | 12 / 11 | -3.7 | No |
554156 | JMV458 | C45H73N13O9 | 940.161 | 11 / 11 | 1.9 | No |
182599 | CHEMBL2431133 | C27H28N4O3 | 456.546 | 7 / 0 | 5.2 | No |
182891 | CHEMBL2431108 | C24H26N4O3 | 418.497 | 6 / 0 | 3.4 | Yes |
186857 | CHEMBL1766941 | C40H68N12O8 | 845.06 | 11 / 9 | -2.0 | No |
190500 | CHEMBL133340 | C38H64N10O8 | 788.992 | 12 / 10 | -0.9 | No |
192162 | CHEMBL132524 | C40H68N12O8 | 845.06 | 14 / 12 | -1.7 | No |
550322 | CHEMBL3954824 | C34H54BrN11O7 | 808.78 | 10 / 9 | -3.1 | No |
196206 | CHEMBL2431111 | C29H32N4O2 | 468.601 | 6 / 0 | 6.3 | No |
196975 | CHEMBL270332 | C76H124N16O14 | 1485.93 | 18 / 16 | 4.4 | No |
197835 | CHEMBL129953 | C40H69N10O8+ | 818.054 | 11 / 9 | -0.4 | No |
198398 | SR142948A | C39H51N5O6 | 685.866 | 8 / 2 | 3.6 | No |
205387 | CHEMBL2431132 | C23H26N4O4S | 454.545 | 8 / 0 | 3.1 | Yes |
461049 | BDBM50342239 | C38H66N12O8 | 819.022 | 11 / 10 | -3.7 | No |
209944 | CHEMBL133798 | C41H71N10O8+ | 832.081 | 11 / 9 | 0.0 | No |
211034 | CHEMBL430910 | C38H64N10O8 | 788.992 | 12 / 10 | -1.0 | No |
550544 | CHEMBL3915284 | C40H65BrN10O8 | 893.926 | 11 / 9 | -1.1 | No |
214680 | CHEMBL1766927 | C35H58N12O8 | 774.925 | 11 / 11 | -4.2 | No |
219625 | CHEMBL2431235 | C27H27N5O4 | 485.544 | 8 / 0 | 5.4 | No |
231750 | CHEMBL2431106 | C25H30N4O2 | 418.541 | 6 / 0 | 4.2 | Yes |
232249 | CHEMBL2431140 | C27H27FN4O2 | 458.537 | 7 / 0 | 5.7 | No |
233713 | CHEMBL335846 | C39H66N10O8 | 803.019 | 12 / 10 | -0.6 | No |
461240 | CHEMBL1172376 | C41H70N9O8+ | 817.066 | 9 / 8 | 2.8 | No |
234477 | CHEMBL2431138 | C28H30N4O3 | 470.573 | 7 / 0 | 5.5 | No |
243562 | CHEMBL337644 | C39H66N10O8 | 803.019 | 12 / 10 | -0.7 | No |
247284 | CHEMBL2431134 | C26H26N4O2 | 426.52 | 6 / 0 | 5.2 | No |
249829 | CHEMBL133850 | C41H70N10O8 | 831.073 | 12 / 9 | 0.3 | No |
250148 | CHEMBL2431112 | C21H24N4O3 | 380.448 | 7 / 0 | 3.5 | Yes |
250156 | CHEMBL1766825 | C39H66N12O8 | 831.033 | 11 / 10 | -2.3 | No |
250879 | CHEMBL254770 | C38H64N8O8 | 760.978 | 11 / 8 | -0.9 | No |
251007 | CHEMBL3099773 | C27H27ClN4O5 | 522.986 | 7 / 2 | 5.1 | No |
251577 | CHEMBL132794 | C42H73N10O8+ | 846.108 | 11 / 9 | 0.3 | No |
256140 | CHEMBL253527 | C39H66N12O8 | 831.033 | 11 / 11 | -3.6 | No |
256347 | NEUROTENSIN | C78H121N21O20 | 1672.95 | 23 / 21 | -3.7 | No |
256846 | CHEMBL2431115 | C23H28N4O3 | 408.502 | 7 / 0 | 4.3 | Yes |
257994 | CHEMBL1766946 | C39H66N8O8 | 775.005 | 11 / 8 | -0.4 | No |
258605 | CHEMBL2431129 | C23H26N4O2 | 390.487 | 6 / 0 | 4.1 | Yes |
259932 | CHEMBL2431122 | C25H30N4O3 | 434.54 | 7 / 0 | 4.9 | Yes |
260434 | CHEMBL439494 | C69H108N20O18 | 1505.74 | 22 / 20 | -7.4 | No |
551174 | CHEMBL3941970 | C34H54BrN9O7 | 780.766 | 10 / 8 | -2.2 | No |
270516 | CHEMBL2431128 | C24H26N4O3 | 418.497 | 7 / 0 | 4.5 | Yes |
273365 | CHEMBL2431232 | C25H30N4O2 | 418.541 | 6 / 0 | 5.0 | Yes |
279995 | CHEMBL2431136 | C26H25FN4O2 | 444.51 | 7 / 0 | 5.3 | No |
551411 | CHEMBL3932989 | C34H54BrN9O7 | 780.766 | 10 / 8 | -2.2 | No |
284031 | CHEMBL2431117 | C24H30N4O3 | 422.529 | 7 / 0 | 4.7 | Yes |
291026 | CHEMBL2431231 | C24H28N4O2 | 404.514 | 6 / 0 | 4.6 | Yes |
291914 | CHEMBL266230 | C39H66N12O8 | 831.033 | 11 / 11 | -2.5 | No |
299167 | CHEMBL2431126 | C24H28N4O2 | 404.514 | 6 / 0 | 4.6 | Yes |
303446 | CHEMBL2431123 | C25H33N5O3 | 451.571 | 8 / 0 | 3.8 | Yes |
305033 | CHEMBL2431238 | C29H32N4O4 | 500.599 | 8 / 0 | 5.5 | No |
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