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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2431118
Molecular formula	C25H32N4O3
IUPAC name	6,7-dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]-2-(2-methylpropyl)quinazoline
Molecular weight	436.556
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	5.1
Synonyms	BDBM50440767 MLS-0471511.0001 SCHEMBL15819842
Inchi Key	JMACYYSITUBWPB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H32N4O3/c1-17(2)14-24-26-19-16-23(32-5)22(31-4)15-18(19)25(27-24)29-12-10-28(11-13-29)20-8-6-7-9-21(20)30-3/h6-9,15-17H,10-14H2,1-5H3
PubChem CID	56593282
ChEMBL	CHEMBL2431118
IUPHAR	N/A
BindingDB	50440767
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
154199	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
154198	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
154200	Neurotensin receptor type 2	O95665	NTSR2	Homo sapiens (Human)	410

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