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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2431233
Molecular formula	C24H27FN4O2
IUPAC name	2-cyclobutyl-4-[4-(2-fluorophenyl)piperazin-1-yl]-6,7-dimethoxyquinazoline
Molecular weight	422.504
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	4.8
Synonyms	BDBM50440764 MLS-0463026.0001 SCHEMBL15819832
Inchi Key	GNFDMFYTUKMSND-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H27FN4O2/c1-30-21-14-17-19(15-22(21)31-2)26-23(16-6-5-7-16)27-24(17)29-12-10-28(11-13-29)20-9-4-3-8-18(20)25/h3-4,8-9,14-16H,5-7,10-13H2,1-2H3
PubChem CID	52914822
ChEMBL	CHEMBL2431233
IUPHAR	N/A
BindingDB	50440764
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
100510	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
100511	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
100509	Neurotensin receptor type 2	O95665	NTSR2	Homo sapiens (Human)	410

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