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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1417160
Molecular formula	C23H27N5O2
IUPAC name	2-cyclobutyl-6,7-dimethoxy-4-(4-pyridin-2-ylpiperazin-1-yl)quinazoline
Molecular weight	405.502
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.9
Synonyms	2-cyclobutyl-6,7-dimethoxy-4-(4-pyridin-2-ylpiperazin-1-yl)quinazoline MLS000699291 AC1LNZT8 SMR000229279 2-cyclobutyl-6,7-dimethoxy-4-[4-(2-pyridinyl)-1-piperazinyl]quinazoline MolPort-019-775-545 BDBM50440758 ZINC33293658 MLS-0232587.0001 SCHEMBL15819960 [ Show all ]
Inchi Key	GPLGXZOMVXBMDO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H27N5O2/c1-29-19-14-17-18(15-20(19)30-2)25-22(16-6-5-7-16)26-23(17)28-12-10-27(11-13-28)21-8-3-4-9-24-21/h3-4,8-9,14-16H,5-7,10-13H2,1-2H3
PubChem CID	1230851
ChEMBL	CHEMBL1417160
IUPHAR	N/A
BindingDB	50440758
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
102077	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
102079	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
102080	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
102078	Neurotensin receptor type 2	O95665	NTSR2	Homo sapiens (Human)	410

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