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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2431106
Molecular formula	C25H30N4O2
IUPAC name	2-cyclopropyl-6,7-dimethoxy-4-[4-[(4-methylphenyl)methyl]piperazin-1-yl]quinazoline
Molecular weight	418.541
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	4.2
Synonyms	SCHEMBL15819681 BDBM50440759 MLS-0471513.0001
Inchi Key	NTOIAIPOJUIVOK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H30N4O2/c1-17-4-6-18(7-5-17)16-28-10-12-29(13-11-28)25-20-14-22(30-2)23(31-3)15-21(20)26-24(27-25)19-8-9-19/h4-7,14-15,19H,8-13,16H2,1-3H3
PubChem CID	56593291
ChEMBL	CHEMBL2431106
IUPHAR	N/A
BindingDB	50440759
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
231751	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
231749	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
231750	Neurotensin receptor type 2	O95665	NTSR2	Homo sapiens (Human)	410

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