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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2431133
Molecular formula	C27H28N4O3
IUPAC name	6,7-dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]-2-phenylquinazoline
Molecular weight	456.546
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	5.2
Synonyms	AC1NF8TN MLS004254797 SMR003080911 MLS-0454791.0001 AKOS005547874 MolPort-000-830-985 1-[4-(2-phenyl-6,7-dimethoxyquinazolin-4-yl)piperazinyl]-2-methoxybenzene STK613295 6,7-dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]-2-phenylquinazoline MLS-0454791.0002 BDBM50440763 SCHEMBL15819136 489416-51-5 MCULE-6614147969 ZINC8738178 [ Show all ]
Inchi Key	LAKZIVWNOULFMV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H28N4O3/c1-32-23-12-8-7-11-22(23)30-13-15-31(16-14-30)27-20-17-24(33-2)25(34-3)18-21(20)28-26(29-27)19-9-5-4-6-10-19/h4-12,17-18H,13-16H2,1-3H3
PubChem CID	4679731
ChEMBL	CHEMBL2431133
IUPHAR	N/A
BindingDB	50440763
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
182600	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
182598	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
182599	Neurotensin receptor type 2	O95665	NTSR2	Homo sapiens (Human)	410

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