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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2431112
Molecular formula	C21H24N4O3
IUPAC name	6,7-dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]quinazoline
Molecular weight	380.448
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.5
Synonyms	MolPort-008-341-882 BDBM50440780 MCULE-6262182369 6,7-dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]quinazoline STK940146 229476-65-7 MLS-0454797.0001 AKOS002365198 ZINC32544286 [ Show all ]
Inchi Key	OTRKBWNAVFQFNL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H24N4O3/c1-26-18-7-5-4-6-17(18)24-8-10-25(11-9-24)21-15-12-19(27-2)20(28-3)13-16(15)22-14-23-21/h4-7,12-14H,8-11H2,1-3H3
PubChem CID	10339735
ChEMBL	CHEMBL2431112
IUPHAR	N/A
BindingDB	50440780
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
250149	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
250147	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
250148	Neurotensin receptor type 2	O95665	NTSR2	Homo sapiens (Human)	410

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