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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Neurotensin receptor type 2
Species	Homo sapiens (Human)
Gene	NTSR2
Synonym	levocabastine-sensitive neurotensin receptor neurotensin receptor type 2 high-affinity levocabastine-sensitive neurotensin receptor NT2R NTR2 NTRL NTS2 receptor NT-R-2 [ Show all ]
Disease	N/A
Length	410
Amino acid sequence	METSSPRPPRPSSNPGLSLDARLGVDTRLWAKVLFTALYALIWALGAAGNALSAHVVLKARAGRAGRLRHHVLSLALAGLLLLLVGVPVELYSFVWFHYPWVFGDLGCRGYYFVHELCAYATVLSVAGLSAERCLAVCQPLRARSLLTPRRTRWLVALSWAASLGLALPMAVIMGQKHELETADGEPEPASRVCTVLVSRTALQVFIQVNVLVSFVLPLALTAFLNGVTVSHLLALCSQVPSTSTPGSSTPSRLELLSEEGLLSFIVWKKTFIQGGQVSLVRHKDVRRIRSLQRSVQVLRAIVVMYVICWLPYHARRLMYCYVPDDAWTDPLYNFYHYFYMVTNTLFYVSSAVTPLLYNAVSSSFRKLFLEAVSSLCGEHHPMKRLPPKPQSPTLMDTASGFGDPPETRT
UniProt	O95665
Protein Data Bank	N/A
GPCR-HGmod model	O95665
3D structure model	This predicted structure model is from GPCR-EXP O95665.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2514
IUPHAR	310
DrugBank	N/A

Ligand

Name	CHEMBL2369509
Molecular formula	C38H64N8O8
IUPAC name	(2S)-2-[[2-[[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-2,6-diaminohexanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]-[(2S)-butan-2-yl]amino]acetyl]amino]-4-methylpentanoic acid
Molecular weight	760.978
Hydrogen bond acceptor	11
Hydrogen bond donor	8
XlogP	-0.8
Synonyms	CHEMBL1766824 (2S)-2-(2-((2S)-2-((S)-1-((S)-6-amino-2-((S)-2,6-diaminohexanamido)hexanoyl)pyrrolidine-2-carboxamido)-N-sec-butyl-3-(4-hydroxyphenyl)propanamido)acetamido)-4-methylpentanoic acid BDBM50342265
Inchi Key	KNEWTNBHAKVQEX-YBEDAUBBSA-N
Inchi ID	InChI=1S/C38H64N8O8/c1-5-25(4)46(23-33(48)42-31(38(53)54)21-24(2)3)37(52)30(22-26-14-16-27(47)17-15-26)44-35(50)32-13-10-20-45(32)36(51)29(12-7-9-19-40)43-34(49)28(41)11-6-8-18-39/h14-17,24-25,28-32,47H,5-13,18-23,39-41H2,1-4H3,(H,42,48)(H,43,49)(H,44,50)(H,53,54)/t25-,28-,29-,30-,31-,32-/m0/s1
PubChem CID	73346899
ChEMBL	CHEMBL2369509
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Ki	330.0 nM	PMID21446649	ChEMBL
Ki	1200.0 nM	PMID21446649	ChEMBL

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