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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3099773
Molecular formula	C27H27ClN4O5
IUPAC name	(2S)-2-[[1-(7-chloroquinolin-4-yl)-2-(2,6-dimethoxyphenyl)imidazole-4-carbonyl]amino]-4-methylpentanoic acid
Molecular weight	522.986
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	5.1
Synonyms	ML301 1531633-84-7 MLS004254788 MLS-0437331.0001 NCGC00386838-01 (2S)-2-{[2-(2,6-dimethoxyphenyl)-1-(7-chloro(4-quinolyl))imidazol-4-yl]carbonylamino}-4-methylpentanoic acid MLS-0437331.0002 BDBM50444943 SMR003080904 [ Show all ]
Inchi Key	OUZUXYQXCXYGMX-IBGZPJMESA-N
Inchi ID	InChI=1S/C27H27ClN4O5/c1-15(2)12-19(27(34)35)31-26(33)20-14-32(21-10-11-29-18-13-16(28)8-9-17(18)21)25(30-20)24-22(36-3)6-5-7-23(24)37-4/h5-11,13-15,19H,12H2,1-4H3,(H,31,33)(H,34,35)/t19-/m0/s1
PubChem CID	49837912
ChEMBL	CHEMBL3099773
IUPHAR	N/A
BindingDB	50444943
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
251008	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
251006	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
251007	Neurotensin receptor type 2	O95665	NTSR2	Homo sapiens (Human)	410

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