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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2431115
Molecular formula	C23H28N4O3
IUPAC name	2-ethyl-6,7-dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]quinazoline
Molecular weight	408.502
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	4.3
Synonyms	2-ethyl-6,7-dimethoxy-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazoline PDEAKHQWPNWDTL-UHFFFAOYSA-N SCHEMBL15818947 BDBM50440753 MLS-0471479.0001
Inchi Key	PDEAKHQWPNWDTL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H28N4O3/c1-5-22-24-17-15-21(30-4)20(29-3)14-16(17)23(25-22)27-12-10-26(11-13-27)18-8-6-7-9-19(18)28-2/h6-9,14-15H,5,10-13H2,1-4H3
PubChem CID	56593293
ChEMBL	CHEMBL2431115
IUPHAR	N/A
BindingDB	50440753
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
256847	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
256845	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
256846	Neurotensin receptor type 2	O95665	NTSR2	Homo sapiens (Human)	410

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