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Name | B2 bradykinin receptor |
---|---|
Species | Cavia porcellus (Guinea pig) |
Gene | BDKRB2 |
Synonym | B2R BK-2 receptor |
Disease | N/A for non-human GPCRs |
Length | 372 |
Amino acid sequence | MFNITSQVSALNATLAQGNSCLDAEWWSWLNTIQAPFLWVLFVLAVLENIFVLSVFFLHKSSCTVAEIYLGNLAVADLILAFGLPFWAITIANNFDWLFGEVLCRMVNTMIQMNMYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCALLLSSPMLVFRTMKDYRDEGHNVTACLIIYPSLTWQVFTNVLLNLVGFLLPLSIITFCTVQIMQVLRNNEMQKFKEIQTERRATVLVLAVLLLFVVCWLPFQIGTFLDTLRLLGFLPGCWEHVIDLITQISSYLAYSNSCLNPLVYVIVGKRFRKKSREVYHGLCRSGGCVSEPAQSENSMGTLRTSISVDRQIHKLQDWARSSSEGTPPGLL |
UniProt | O70526 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4111 |
IUPHAR | N/A |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
684 | CHEMBL434667 | C15H10Cl3N3O | 354.615 | 2 / 1 | 5.2 | No |
1064 | CHEMBL544720 | C39H39ClN4O4 | 663.215 | 5 / 3 | N/A | No |
1386 | CHEMBL112991 | C28H22Cl2F3N3O3S | 608.457 | 8 / 1 | 7.2 | No |
1766 | CHEMBL346718 | C21H21BrCl2N4O3 | 528.228 | 4 / 0 | 4.8 | No |
2304 | CHEMBL542473 | C26H25BrCl3N5O4 | 657.771 | 5 / 3 | N/A | No |
3091 | CHEMBL538281 | C28H26BrCl2N5O5S | 695.41 | 7 / 2 | 5.7 | No |
3418 | CHEMBL114732 | C28H25Cl2N3O4S | 570.485 | 6 / 1 | 6.3 | No |
4299 | CHEMBL342195 | C32H32N4O4 | 536.632 | 5 / 2 | 4.5 | No |
4434 | CHEMBL554206 | C30H28Cl3N5O4 | 628.935 | 6 / 3 | N/A | No |
4521 | CHEMBL140383 | C37H35N3O3 | 569.705 | 4 / 2 | 6.9 | No |
557419 | B-9858 | C64H95N15O13 | 1282.56 | 17 / 14 | -3.3 | No |
5038 | Lys-Lys-Arg-Pro-Hyp-Gly-Igl-Ser-D-Igl-Oic | C64H95N15O13 | 1282.56 | 17 / 14 | -3.3 | No |
7480 | CHEMBL542096 | C31H29Cl3N4O4 | 627.947 | 5 / 3 | N/A | No |
10791 | CHEMBL544601 | C29H26Cl3N3O3 | 570.895 | 4 / 2 | N/A | No |
15294 | CHEMBL156606 | C15H12Cl2N2O | 307.174 | 2 / 0 | 4.9 | Yes |
15392 | CHEMBL154188 | C20H19BrCl2N4O3 | 514.201 | 4 / 1 | 4.6 | No |
17269 | CHEMBL156847 | C18H15BrCl3N3O2 | 491.591 | 3 / 0 | 5.9 | No |
18031 | CHEMBL2370038 | C63H95N19O13 | 1326.57 | 17 / 13 | -5.7 | No |
18144 | CHEMBL132510 | C31H31Cl2N5O5 | 624.519 | 6 / 1 | 4.7 | No |
18679 | CHEMBL112360 | C32H33N3O5 | 539.632 | 6 / 1 | 5.2 | No |
24530 | CHEMBL542598 | C36H31Cl3N8O4 | 746.046 | 7 / 4 | N/A | No |
24700 | CHEMBL1956722 | C36H48Cl2N5O6S+ | 749.769 | 8 / 1 | 4.3 | No |
27103 | CHEMBL553293 | C33H30Cl2N4O4 | 617.527 | 5 / 1 | 5.5 | No |
27305 | CHEMBL540840 | C28H27BrCl4N6O4 | 733.266 | 6 / 4 | N/A | No |
33937 | CHEMBL325742 | C26H23Cl2N3O4S | 544.447 | 6 / 1 | 6.1 | No |
34875 | CHEMBL3143958 | C34H37Cl4N5O4 | 721.501 | 6 / 3 | N/A | No |
34897 | CHEMBL98292 | C32H32Cl2N6O7 | 683.543 | 9 / 2 | 4.1 | No |
35703 | CHEMBL542836 | C31H31Cl2N5O4 | 608.52 | 5 / 2 | 5.1 | No |
35886 | CHEMBL43746 | C31H31Cl2N5O4 | 608.52 | 5 / 2 | 4.9 | No |
35949 | CHEMBL205093 | C34H46Cl2N6O5S | 721.739 | 9 / 2 | 3.8 | No |
36161 | CHEMBL553844 | C28H27BrCl4N6O4 | 733.266 | 6 / 4 | N/A | No |
36349 | CHEMBL539792 | C40H39Cl3N6O4 | 774.14 | 7 / 3 | N/A | No |
37706 | CHEMBL556176 | C20H20BrCl2N5O3 | 529.216 | 4 / 2 | 4.4 | No |
38103 | CHEMBL543068 | C41H34Cl3N7O3 | 779.119 | 6 / 3 | N/A | No |
39071 | CHEMBL357075 | C49H41N7O3 | 775.913 | 8 / 1 | 7.4 | No |
39072 | CHEMBL154633 | C18H18BrCl2N3O | 443.166 | 3 / 0 | 6.4 | No |
41223 | CHEMBL153890 | C16H14Cl2N2O2 | 337.2 | 3 / 1 | 4.0 | Yes |
42911 | CHEMBL543659 | C34H31Cl5N6O4 | 764.91 | 7 / 5 | N/A | No |
45270 | CHEMBL538732 | C29H27BrCl3N5O4 | 695.82 | 5 / 3 | N/A | No |
46266 | CHEMBL113176 | C32H30F3N3O4S | 609.664 | 9 / 1 | 6.2 | No |
46601 | CHEMBL267493 | C35H46Cl2N8O5S | 761.764 | 9 / 4 | 2.7 | No |
47388 | CHEMBL538020 | C35H36Cl3N5O6 | 729.052 | 7 / 3 | N/A | No |
49163 | CHEMBL133186 | C32H31Cl2N5O4 | 620.531 | 5 / 2 | 5.2 | No |
49574 | CHEMBL375576 | C34H44Cl2N6O5S | 719.723 | 9 / 3 | 3.3 | No |
51680 | CHEMBL544600 | C26H24BrCl3N4O3 | 626.757 | 4 / 2 | N/A | No |
54765 | CHEMBL555465 | C30H27Cl2N5O4 | 592.477 | 6 / 2 | 4.3 | No |
60167 | CHEMBL2028979 | C60H91N19O12 | 1270.51 | 16 / 15 | -4.9 | No |
60959 | CHEMBL543898 | C27H24BrCl3N4O3 | 638.768 | 4 / 2 | N/A | No |
65298 | CHEMBL410363 | C57H81N13O12 | 1140.35 | 14 / 12 | -1.3 | No |
66596 | CHEMBL543899 | C30H29BrCl3N5O4 | 709.847 | 5 / 2 | N/A | No |
70566 | CHEMBL537927 | C40H39Cl3N6O4 | 774.14 | 7 / 3 | N/A | No |
70840 | CHEMBL325601 | C29H35N3O6S | 553.674 | 8 / 1 | 3.7 | No |
71946 | CHEMBL358232 | C25H23N3O | 381.479 | 3 / 0 | 4.9 | Yes |
75137 | CHEMBL133005 | C36H30Cl2N4O4 | 653.56 | 5 / 2 | 6.9 | No |
76377 | CHEMBL553315 | C43H43ClN6O5 | 759.304 | 6 / 2 | N/A | No |
76672 | CHEMBL131647 | C43H68N12O8 | 881.093 | 11 / 10 | -2.4 | No |
76816 | CHEMBL329758 | C31H32Cl2N6O6 | 655.533 | 8 / 2 | 3.5 | No |
77204 | CHEMBL134028 | C31H28Cl2N4O4 | 591.489 | 5 / 2 | 5.4 | No |
78627 | CHEMBL154393 | C15H11BrCl2N2O | 386.07 | 2 / 0 | 5.9 | No |
78963 | CHEMBL552543 | C35H36N4O4 | 576.697 | 5 / 1 | 5.0 | No |
79007 | CHEMBL154130 | C21H21BrCl2N4O3 | 528.228 | 4 / 1 | 5.0 | No |
79375 | CHEMBL221683 | C35H46Cl2N5O5S+ | 719.743 | 7 / 1 | 4.8 | No |
79834 | CHEMBL3215999 | C37H41Cl6N5O5 | 848.465 | 7 / 5 | N/A | No |
80744 | CHEMBL538531 | C30H29BrCl3N5O4 | 709.847 | 5 / 2 | N/A | No |
82098 | CHEMBL131263 | C32H30Cl2N4O4 | 605.516 | 5 / 1 | 5.6 | No |
84588 | CHEMBL555202 | C34H28Cl2N6O4 | 655.536 | 7 / 2 | 5.1 | No |
85130 | Fasitibant | C36H49Cl2N6O6S+ | 764.784 | 9 / 2 | 3.5 | No |
85497 | CHEMBL545765 | C25H22BrCl3N6O5 | 672.742 | 6 / 3 | N/A | No |
85656 | CHEMBL298463 | C30H27Cl2N5O4 | 592.477 | 6 / 2 | 4.7 | No |
85999 | CHEMBL542232 | C30H29Cl4N5O4 | 665.393 | 6 / 4 | N/A | No |
86536 | CHEMBL424268 | C31H32N6O4 | 552.635 | 7 / 2 | 3.0 | No |
88160 | CHEMBL264259 | C35H31Cl2N5O4 | 656.564 | 5 / 2 | 5.9 | No |
88814 | CHEMBL380273 | C33H44Cl2N6O5S | 707.712 | 9 / 2 | 3.9 | No |
90855 | CHEMBL1793829 | C55H80N14O11S | 1145.39 | 16 / 11 | -3.7 | No |
92645 | CHEMBL544132 | C27H24BrCl2N5O4 | 633.324 | 5 / 2 | 5.7 | No |
92824 | CHEMBL553614 | C32H29Cl2N5O4 | 618.515 | 6 / 1 | 4.8 | No |
93060 | CHEMBL436418 | C15H9Cl2F3N2O | 361.145 | 5 / 0 | 5.4 | No |
94220 | CHEMBL130775 | C35H33N3O3S | 575.727 | 5 / 2 | 6.6 | No |
94839 | CHEMBL3216880 | C34H34Cl6N6O4 | 803.384 | 6 / 6 | N/A | No |
96539 | CHEMBL3215979 | C34H34Cl6N6O4 | 803.384 | 6 / 6 | N/A | No |
96902 | CHEMBL154570 | C15H10BrCl2N3O | 399.069 | 2 / 1 | 5.3 | No |
97336 | CHEMBL544623 | C51H41N7O2 | 783.936 | 7 / 1 | 8.3 | No |
99033 | CHEMBL538784 | C34H35N7O6 | 637.697 | 8 / 4 | 1.9 | No |
102653 | CHEMBL338682 | C24H27BrCl2N4O3 | 570.309 | 4 / 1 | 6.5 | No |
102674 | CHEMBL553293 | C33H31Cl3N4O4 | 653.985 | 5 / 2 | N/A | No |
102804 | CHEMBL344021 | C33H34N4O6 | 582.657 | 7 / 2 | 4.1 | No |
103219 | CHEMBL249235 | C34H45Cl2N7O4S | 718.739 | 8 / 2 | 4.4 | No |
104279 | CHEMBL113502 | C25H27N5O4 | 461.522 | 6 / 2 | 2.6 | Yes |
104839 | CHEMBL543898 | C27H23BrCl2N4O3 | 602.31 | 4 / 1 | 6.7 | No |
104846 | CHEMBL537683 | C40H42N6O5 | 686.813 | 6 / 1 | 4.1 | No |
110594 | CHEMBL154386 | C15H11BrCl2N2O | 386.07 | 2 / 0 | 5.9 | No |
111776 | CHEMBL541590 | C32H35Cl2N5O4 | 624.563 | 6 / 4 | N/A | No |
115604 | CHEMBL553843 | C32H35Cl2N5O4 | 624.563 | 6 / 4 | N/A | No |
116131 | CHEMBL554431 | C23H26BrCl3N4O3 | 592.74 | 4 / 2 | N/A | No |
116181 | CHEMBL130452 | C27H25BrCl2N4O3 | 604.326 | 4 / 1 | 6.5 | No |
116663 | CHEMBL376866 | C35H47Cl2N6O5S+ | 734.758 | 8 / 2 | 4.0 | No |
117021 | CHEMBL556816 | C25H21BrCl3N5O3 | 625.729 | 4 / 2 | 6.6 | No |
119549 | CHEMBL540840 | C28H25BrCl2N6O4 | 660.35 | 6 / 2 | 5.1 | No |
121289 | CHEMBL544622 | C38H42N6O6 | 678.79 | 7 / 1 | 3.2 | No |
121345 | CHEMBL154682 | C20H18BrCl2N3O4 | 515.185 | 5 / 0 | 5.2 | No |
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