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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	B2 bradykinin receptor
Species	Cavia porcellus (Guinea pig)
Gene	BDKRB2
Synonym	B2R BK-2 receptor
Disease	N/A for non-human GPCRs
Length	372
Amino acid sequence	MFNITSQVSALNATLAQGNSCLDAEWWSWLNTIQAPFLWVLFVLAVLENIFVLSVFFLHKSSCTVAEIYLGNLAVADLILAFGLPFWAITIANNFDWLFGEVLCRMVNTMIQMNMYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCALLLSSPMLVFRTMKDYRDEGHNVTACLIIYPSLTWQVFTNVLLNLVGFLLPLSIITFCTVQIMQVLRNNEMQKFKEIQTERRATVLVLAVLLLFVVCWLPFQIGTFLDTLRLLGFLPGCWEHVIDLITQISSYLAYSNSCLNPLVYVIVGKRFRKKSREVYHGLCRSGGCVSEPAQSENSMGTLRTSISVDRQIHKLQDWARSSSEGTPPGLL
UniProt	O70526
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4111
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL156847
Molecular formula	C18H15BrCl3N3O2
IUPAC name	N-[3-[(3-bromo-2-methylimidazo[1,2-a]pyridin-8-yl)oxymethyl]-2,4,6-trichlorophenyl]-N-methylacetamide
Molecular weight	491.591
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	5.9
Synonyms	N-[3-(3-Bromo-2-methyl-imidazo[1,2-a]pyridin-8-yloxymethyl)-2,4,6-trichloro-phenyl]-N-methyl-acetamide SCHEMBL8564293 BDBM50062888 N-Methyl-N-[2,4,6-trichloro-3-[(2-methyl-3-bromoimidazo[1,2-a]pyridin-8-yl)oxymethyl]phenyl]acetamide
Inchi Key	AYAKZDWRFVQFCP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H15BrCl3N3O2/c1-9-17(19)25-6-4-5-14(18(25)23-9)27-8-11-12(20)7-13(21)16(15(11)22)24(3)10(2)26/h4-7H,8H2,1-3H3
PubChem CID	11799290
ChEMBL	CHEMBL156847
IUPHAR	N/A
BindingDB	50062888
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	420.0 nM	PMID9484506	BindingDB,ChEMBL

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