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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	B2 bradykinin receptor
Species	Cavia porcellus (Guinea pig)
Gene	BDKRB2
Synonym	B2R BK-2 receptor
Disease	N/A for non-human GPCRs
Length	372
Amino acid sequence	MFNITSQVSALNATLAQGNSCLDAEWWSWLNTIQAPFLWVLFVLAVLENIFVLSVFFLHKSSCTVAEIYLGNLAVADLILAFGLPFWAITIANNFDWLFGEVLCRMVNTMIQMNMYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCALLLSSPMLVFRTMKDYRDEGHNVTACLIIYPSLTWQVFTNVLLNLVGFLLPLSIITFCTVQIMQVLRNNEMQKFKEIQTERRATVLVLAVLLLFVVCWLPFQIGTFLDTLRLLGFLPGCWEHVIDLITQISSYLAYSNSCLNPLVYVIVGKRFRKKSREVYHGLCRSGGCVSEPAQSENSMGTLRTSISVDRQIHKLQDWARSSSEGTPPGLL
UniProt	O70526
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4111
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL436418
Molecular formula	C15H9Cl2F3N2O
IUPAC name	8-[(2,6-dichlorophenyl)methoxy]-2-(trifluoromethyl)imidazo[1,2-a]pyridine
Molecular weight	361.145
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	5.4
Synonyms	BDBM50062874 GCLUMSJIBNPQNB-UHFFFAOYSA-N 8-(2,6-Dichloro-benzyloxy)-2-trifluoromethyl-imidazo[1,2-a]pyridine SCHEMBL8566754 8-(2,6-dichlorobenzyloxy)-2-trifluoromethylimidazo[1,2-a]pyridine
Inchi Key	GCLUMSJIBNPQNB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H9Cl2F3N2O/c16-10-3-1-4-11(17)9(10)8-23-12-5-2-6-22-7-13(15(18,19)20)21-14(12)22/h1-7H,8H2
PubChem CID	10594718
ChEMBL	CHEMBL436418
IUPHAR	N/A
BindingDB	50062874
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<100000.0 nM	PMID9484506	BindingDB,ChEMBL

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