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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
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GPCR

Name	B2 bradykinin receptor
Species	Cavia porcellus (Guinea pig)
Gene	BDKRB2
Synonym	B2R BK-2 receptor
Disease	N/A for non-human GPCRs
Length	372
Amino acid sequence	MFNITSQVSALNATLAQGNSCLDAEWWSWLNTIQAPFLWVLFVLAVLENIFVLSVFFLHKSSCTVAEIYLGNLAVADLILAFGLPFWAITIANNFDWLFGEVLCRMVNTMIQMNMYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCALLLSSPMLVFRTMKDYRDEGHNVTACLIIYPSLTWQVFTNVLLNLVGFLLPLSIITFCTVQIMQVLRNNEMQKFKEIQTERRATVLVLAVLLLFVVCWLPFQIGTFLDTLRLLGFLPGCWEHVIDLITQISSYLAYSNSCLNPLVYVIVGKRFRKKSREVYHGLCRSGGCVSEPAQSENSMGTLRTSISVDRQIHKLQDWARSSSEGTPPGLL
UniProt	O70526
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4111
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL156606
Molecular formula	C15H12Cl2N2O
IUPAC name	8-[(2,6-dichlorophenyl)methoxy]-2-methylimidazo[1,2-a]pyridine
Molecular weight	307.174
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	4.9
Synonyms	2-Methyl-8-(2,6-dichlorobenzyloxy)imidazo[1,2-a]pyridine SCHEMBL8562316 8-(2,6-dichlorobenzyloxy)-2-methylimidazo[1,2-a]pyridine AVHIPWAYBTVFDM-UHFFFAOYSA-N 8-(2,6-Dichloro-benzyloxy)-2-methyl-imidazo[1,2-a]pyridine BDBM50062866 [ Show all ]
Inchi Key	AVHIPWAYBTVFDM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H12Cl2N2O/c1-10-8-19-7-3-6-14(15(19)18-10)20-9-11-12(16)4-2-5-13(11)17/h2-8H,9H2,1H3
PubChem CID	10852230
ChEMBL	CHEMBL156606
IUPHAR	N/A
BindingDB	50062866
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	4500.0 nM	PMID9484506	BindingDB,ChEMBL

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