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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	sotalol
Molecular formula	C12H20N2O3S
IUPAC name	N-[4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl]methanesulfonamide
Molecular weight	272.363
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	0.2
Synonyms	GTPL7297 Methanesulfonamide, N-(4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)phenyl)-(9CI) N-(4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenyl)methanesulfonamide NCGC00015919-06 4'-[1-Hhydroxy-2-(isopropylamino)ethyl]methanesulfonanilide R2742 AB00514715_11 Sotalol Monohydrochloride AX8014256 ST24048357 C-17160 d,l-Sotalol DSSTox_CID_3589 L013427 MJ-1999 N-{4-[1-hydroxy-2-(isopropylamino)ethyl]phenyl}methanesulfonamide NCGC00024899-03 930S209 Sorine AC1L1JXU Sotalol,(-) Betapace AF (TN) ZBMZVLHSJCTVON-UHFFFAOYSA-N CAS-3930-20-9 Darob mite DTXSID0023589 Methanesulfonamide, N-(4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)phenyl)- N-(4-[1-Hydroxy-2-(isopropylamino)ethyl]phenyl)methanesulfonamide # NCGC00015919-04 4'-(1-Hydroxy-2-(isopropylamino)ethyl)methane sulfonanilide Prestwick2_000966 AB00514715-09 ALBB-022454 Sotalolum [INN-Latin] BRD-A33168282-003-06-5 CCRIS 4204 CHEMBL471 DB00489 HMS2089K09 Methanesulfonamide, N-[4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]- N-[4-[1-Hydroxy-2-(isopropylamino)ethyl]phenyl]methanesulfonamide (+-)-Sotalol NCGC00015919-07 4'-[1-Hydroxy-2-(isopropylamino)ethyl]metahnesulfonanilide SBI-0051025.P002 AB00514715_12 Sotalol [INN:BAN] BDBM25762 Tox21_110261 C07309 D04VMT DSSTox_GSID_23589 Lopac0_001055 MolPort-002-042-381 N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide 27948-47-6 Prestwick0_000966 959-24-0 (mono-hydrochloride) Sotacor (TN) AK129841 Sotalolo BPBio1_001069 ZX-AN038039 CC-34512 Darob mite (TN) FT-0635062 Methanesulfonamide, N-(4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)phenyl)- (9CI) N-(4-{1-hydroxy-2-[(1-methylethyl)amino]ethyl}phenyl)methanesulfonamide NCGC00015919-05 4'-(1-Hydroxy-2-isopropylaminoethyl)methanesulfonanilid Prestwick3_000966 AB00514715-10 Sotalol (INN) API0004211 SPBio_002892 BSPBio_000971 CHEBI:63622 cid_66245 DL-Sotalol KB-258172 Methanesulfonanilide, 4'-(1-hydroxy-2-(isopropylamino)ethyl)- N-[4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl]methanesulfonamide .beta.-Cardone NCGC00024899-02 4'-[1-Hydroxy-2-(isopropylamino)ethyl]methanesulfonanilide SCHEMBL16407 AC-19021 Sotalol,(+) beta-Cardone VA11777 C12H20N2O3S D08525 DSSTox_RID_77096 LS-90249 N-(4-(1-Hydroxy-2-(isopropylamino)ethyl)phenyl)methanesulfonamide NCGC00015919-03 3930-20-9 Prestwick1_000966 AB00514715 Sotalex (TN) AKOS015897340 Sotalolum BRD-A33168282-003-03-2 CCG-205132 [ Show all ]
Inchi Key	ZBMZVLHSJCTVON-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3
PubChem CID	5253
ChEMBL	CHEMBL471
IUPHAR	N/A
BindingDB	25762
DrugBank	DB00489
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
424453	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
424450	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
424452	Beta-1 adrenergic receptor	P18090	Adrb1	Rattus norvegicus (Rat)	466
424448	Beta-2 adrenergic receptor	Q28044	ADRB2	Bos taurus (Bovine)	418
424449	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
424451	Beta-2 adrenergic receptor	P54833	ADRB2	Canis lupus familiaris (Dog)	415
462810	Beta-2 adrenergic receptor	P10608	Adrb2	Rattus norvegicus (Rat)	418
424454	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408

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