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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	201943-63-7
Molecular formula	C20H19NO5
IUPAC name	(1S,2S)-2-[(1S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]cyclopropane-1-carboxylic acid
Molecular weight	353.374
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	-0.2
Synonyms	LY 341495 RL02516 (S)-2-[(S)-1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cyclopropanecarboxylic acid ABP000453 BC638757 GTPL1378 LY-341495 SR-01000597370 (1S,2S)-2-[(1S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]cyclopropane-1-carboxylic acid 2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cyclopropanecarboxylic acid(LY341495) BRD-K69763916-001-01-7 HY-70059 MolPort-023-276-045 Z99 (1S,2S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cyclopropanecarboxylic acid CHEMBL432038 LY 341495;LY-341495 SB17024 (1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl)cyclopropane-1-carboxylic acid 2(S)-Amino-2-[2(S)-carboxy-1(S)-cyclopropyl]-3-(9H-xanthen-9-yl)propionic acid AKOS024456466 BCP9000885 GTPL1399 LY341495 SR-01000597370-1 (1S,2S)-2-[(1S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]cyclopropanecarboxylic acid CHEBI:93224 J-501015 NCGC00025041-02 ZINC3826602 (2S)-2-AMINO-2-[(1S,2S)-2-CARBOXYCYCLOPROP-1-YL]-3-(XANTH-9-YL) PROPANOIC ACID 618093-20-2 CS-0343 LY-341,495 SCHEMBL481153 (1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl)cyclopropanecarboxylic acid 2-[(1s,2s)-2-Carboxycyclopropyl]-3-(9h-Xanthen-9-Yl)-D-Alanine API0006790 BDBM50062522 HMS3267B15 LY341495 /LY-341495 W-5248 (1S,2S)-2-[(S)-1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cyclopropanecarboxylic acid 3794AH [ Show all ]
Inchi Key	VLZBRVJVCCNPRJ-KPHUOKFYSA-N
Inchi ID	InChI=1S/C20H19NO5/c21-20(19(24)25,15-9-13(15)18(22)23)10-14-11-5-1-3-7-16(11)26-17-8-4-2-6-12(14)17/h1-8,13-15H,9-10,21H2,(H,22,23)(H,24,25)/t13-,15-,20-/m0/s1
PubChem CID	9819927
ChEMBL	CHEMBL432038
IUPHAR	N/A
BindingDB	50062522
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
358349	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
358357	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
358348	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
358354	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
358346	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
358350	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
358353	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
358358	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
358345	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
358347	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
358356	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871
358352	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
358355	Metabotropic glutamate receptor 7	P35400	Grm7	Rattus norvegicus (Rat)	915
358351	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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