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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	N6-Cyclohexyladenosine
Molecular formula	C16H23N5O4
IUPAC name	(2R,3R,4S,5R)-2-[6-(cyclohexylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Molecular weight	349.391
Hydrogen bond acceptor	8
Hydrogen bond donor	4
XlogP	1.4
Synonyms	C16H23N5O4 HMS3261C03 N-6-cyclohexyladenosine NCGC00093771-03 PDSP2_001009 4616AB Adenosine, N-cyclohexyl- CHEMBL45891 Lopac0_000331 PDSP1_000670 SR-01000075797-1 (2R,3R,4S,5R)-2-(6-(Cyclohexylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol BDBM50009552 EU-0100331 MolPort-027-835-536 NCGC00093771-01 PDSP2_000660 Tox21_500331 36396-99-3 CCG-204426 HY-18939 n-cyclohexyladenosine NCGC00093771-04 SCHEMBL145856 AJ-48997 CS-5050 LP00331 N6-Cyclohexylado (CHA) PDSP1_001023 ST24026156 (2R,3R,4S,5R)-2-[6-(cyclohexylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol C 9901 GTPL423 N(6)-Cyclohexyladenosine NCGC00093771-02 PDSP2_001007 ZINC4217017 KB-206469 N6 -cyclohexyladenosine NCGC00261016-01 SR-01000075797 AC-27401 AKOS016009588 D02JCM MFCD00036808 n6-cyclohexyl[3h]adenosine PDSP1_001025 SZBULDQSDUXAPJ-XNIJJKJLSA-N 2-[6-Amino-2-(2-morpholin-4-yl-ethylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol [ Show all ]
Inchi Key	SZBULDQSDUXAPJ-XNIJJKJLSA-N
Inchi ID	InChI=1S/C16H23N5O4/c22-6-10-12(23)13(24)16(25-10)21-8-19-11-14(17-7-18-15(11)21)20-9-4-2-1-3-5-9/h7-10,12-13,16,22-24H,1-6H2,(H,17,18,20)/t10-,12-,13-,16-/m1/s1
PubChem CID	9841284
ChEMBL	CHEMBL45891
IUPHAR	423
BindingDB	50009552
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
326766	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
326774	Adenosine receptor A1	P28190	ADORA1	Bos taurus (Bovine)	326
326776	Adenosine receptor A1	P49892	ADORA1	Gallus gallus (Chicken)	324
326777	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
326767	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
326768	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410
326771	Adenosine receptor A2a	P46616	ADORA2A	Cavia porcellus (Guinea pig)	409
326772	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332
326769	Adenosine receptor A3	P28647	Adora3	Rattus norvegicus (Rat)	320
554882	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318
326773	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
326775	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446

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