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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL483993
Molecular formula	C22H31N5O3
IUPAC name	8-(4-methoxy-2,5-dimethylphenyl)-N,N-bis(2-methoxyethyl)-2,7-dimethylpyrazolo[1,5-a][1,3,5]triazin-4-amine
Molecular weight	413.522
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.4
Synonyms	BDBM29464 Pyrazolo[1,5-a]-1,3,5-triazine, 12-33
Inchi Key	RPKIJOOZVCXURK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H31N5O3/c1-14-13-19(30-7)15(2)12-18(14)20-16(3)25-27-21(20)23-17(4)24-22(27)26(8-10-28-5)9-11-29-6/h12-13H,8-11H2,1-7H3
PubChem CID	42618195
ChEMBL	CHEMBL483993
IUPHAR	N/A
BindingDB	29464
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
301926	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
301922	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
301921	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
301925	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
301919	Corticotropin-releasing factor receptor 1	P35353	Crhr1	Rattus norvegicus (Rat)	415
301923	Corticotropin-releasing factor receptor 1	P34998	CRHR1	Homo sapiens (Human)	444
301918	Corticotropin-releasing factor receptor 2	Q13324	CRHR2	Homo sapiens (Human)	411
301920	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
301927	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
301924	Vasopressin V1a receptor	P37288	AVPR1A	Homo sapiens (Human)	418

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