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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Tocris-1052
Molecular formula	C14H19N3O3S
IUPAC name	N-[(5R)-5-(4,5-dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl]methanesulfonamide
Molecular weight	309.384
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	0.4
Synonyms	(R)-A-61603 CHEMBL336161 AC1O7GWA N-[(5R)-5-(4,5-dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl]methanesulfonamide ZINC2581459 NCGC00024968-01 [ Show all ]
Inchi Key	OQFCXJDXHCDLHX-LLVKDONJSA-N
Inchi ID	InChI=1S/C14H19N3O3S/c1-21(19,20)17-13-10-3-2-4-11(14-15-7-8-16-14)9(10)5-6-12(13)18/h5-6,11,17-18H,2-4,7-8H2,1H3,(H,15,16)/t11-/m1/s1
PubChem CID	6604803
ChEMBL	CHEMBL336161
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
247697	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
247699	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
247701	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
247698	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
247700	Alpha-1B adrenergic receptor	P18841	ADRA1B	Mesocricetus auratus (Golden hamster)	515
247696	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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