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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL315268
Molecular formula	C8H12N2O4
IUPAC name	(2S)-2-amino-4-(5-methyl-3-oxo-1,2-oxazol-4-yl)butanoic acid
Molecular weight	200.194
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	-2.9
Synonyms	(S)-2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acid 2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acid SCHEMBL12506417 AC1O7GW0 (s)-2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid 2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acid(S-homo-AMPA) Tocris-1026 BDBM50060719 (2S)-2-amino-4-(5-methyl-3-oxo-1,2-oxazol-4-yl)butanoic acid NCGC00024946-01 (S)-Homo-AMPA [ Show all ]
Inchi Key	NZDIZJGEDFARSV-LURJTMIESA-N
Inchi ID	InChI=1S/C8H12N2O4/c1-4-5(7(11)10-14-4)2-3-6(9)8(12)13/h6H,2-3,9H2,1H3,(H,10,11)(H,12,13)/t6-/m0/s1
PubChem CID	6604795
ChEMBL	CHEMBL315268
IUPHAR	N/A
BindingDB	50060719
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
235579	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
235585	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
235577	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
235578	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
235576	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
235582	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
235584	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
235589	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
235580	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
235583	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
235581	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
235588	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871
235586	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
235587	Metabotropic glutamate receptor 7	P35400	Grm7	Rattus norvegicus (Rat)	915

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