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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MK-0354
Molecular formula	C7H8N6
IUPAC name	3-(2H-tetrazol-5-yl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole
Molecular weight	176.183
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	0.2
Synonyms	1,4,5,6-Tetrahydro-3-(1H-tetrazol-5-yl)cyclopenta[c]pyrazole 4U62D8JYIQ HY-13008 SCHEMBL1875705 3-(1H-tetrazol-5-yl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole Cyclopenta(C)pyrazole, 1,4,5,6-tetrahydro-3-(1H-tetrazol-5-yl)- MK 0354 3-(2H-tetrazol-5-yl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole BCP18112 NCGC00263122-01 1,4,5,6-Tetrahydro-3-(1H-tetrazol-5-yl)cyclopenta[c]pyrazole(MK-0354) 5-{1H,4H,5H,6H-CYCLOPENTA[C]PYRAZOL-3-YL}-1H-1,2,3,4-TETRAZOLE CHEMBL456145 KB-78878 UNII-4U62D8JYIQ 3-(2H-tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole 851776-28-8 D0A5MR 3-(2H-tetrazol-5-yl)-1,4,5,6-tetrahydrocyclopenta[d]pyrazole BDBM50273099 GTPL5784 NCGC00263122-02 1,4,5,6-tetrahydro-3-(2H-tetrazol-5-yl)Cyclopentapyrazole CS-4589 LTQYSJKGRPGMPO-UHFFFAOYSA-N ZINC38312374 3-(2H-tetrazol-5-yl)-1,4,5,6-tetrahydrocyclopentapyrazole AKOS030526928 DA-02747 MolPort-009-683-033 [ Show all ]
Inchi Key	LTQYSJKGRPGMPO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C7H8N6/c1-2-4-5(3-1)8-9-6(4)7-10-12-13-11-7/h1-3H2,(H,8,9)(H,10,11,12,13)
PubChem CID	11159621
ChEMBL	CHEMBL456145
IUPHAR	5784
BindingDB	50273099
DrugBank	DB05939
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
550328	G-protein coupled estrogen receptor 1	Q99527	GPER1	Homo sapiens (Human)	375
196138	Hydroxycarboxylic acid receptor 2	Q80Z39	Hcar2	Rattus norvegicus (Rat)	360
196139	Hydroxycarboxylic acid receptor 2	Q9EP66	Hcar2	Mus musculus (Mouse)	360
196140	Hydroxycarboxylic acid receptor 2	Q8TDS4	HCAR2	Homo sapiens (Human)	363

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